Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark

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Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark. / Jørgensen, Anja; Bjørn-Mortensen, Karen; Graff Jensen, Sidse; Sloth Andersen, Ellen; Ravn, Pernille.

I: Infectious Diseases, Bind 53, Nr. 3, 2021, s. 196-200.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jørgensen, A, Bjørn-Mortensen, K, Graff Jensen, S, Sloth Andersen, E & Ravn, P 2021, 'Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark', Infectious Diseases, bind 53, nr. 3, s. 196-200. https://doi.org/10.1080/23744235.2020.1865562

APA

Jørgensen, A., Bjørn-Mortensen, K., Graff Jensen, S., Sloth Andersen, E., & Ravn, P. (2021). Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark. Infectious Diseases, 53(3), 196-200. https://doi.org/10.1080/23744235.2020.1865562

Vancouver

Jørgensen A, Bjørn-Mortensen K, Graff Jensen S, Sloth Andersen E, Ravn P. Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark. Infectious Diseases. 2021;53(3):196-200. https://doi.org/10.1080/23744235.2020.1865562

Author

Jørgensen, Anja ; Bjørn-Mortensen, Karen ; Graff Jensen, Sidse ; Sloth Andersen, Ellen ; Ravn, Pernille. / Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark. I: Infectious Diseases. 2021 ; Bind 53, Nr. 3. s. 196-200.

Bibtex

@article{d34680b0718e4f4893b409b1483d8f0a,

title = "Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark",

abstract = "Background: Denmark is a low-prevalence country for tuberculosis (TB), hepatitis B (HBV), and hepatitis C (HCV) but the three diseases have similar sociodemographic risk factors. We estimated the prevalence and possible risk factors of HBV and HCV among TB-patients in a large TB clinic in Denmark. Methods: All patients starting anti-TB-treatment at Copenhagen University Hospital, Herlev-Gentofte from April 1st 2018 through June 1st 2019 were included. Results from HBV and HCV testing as well as sociodemographic information were collected. Risk factor analyses were carried out using descriptive statistics. Results: Of 82 patients tested for HBV, one (1.2%) had chronic HBV and 16 (19.5%) had serocleared HBV. Of 91 patients tested for HCV, three (3.3%) had chronic HCV and one (1.1%) had serocleared HCV. Country of origin other than Denmark was significantly associated with HBV-seropositivity among TB-patients, particularly patients from Greenland, Asia, Africa and Eastern Europe. No other significantly associated risk factors were found. Conclusion: The prevalences of chronic and prior HBV and HCV among TB-patients were lower compared to studies in TB high endemic areas but higher than those found in the Danish background population. We calculated the number needed to test to find one patient with HBV ranged between 27 and 83 and we suggest continuing screening of chronic HBV and HCV in TB-patients in Denmark.",

keywords = "Denmark, hepatitis B, hepatitis C, risk factors, Tuberculosis",

author = "Anja J{\o}rgensen and Karen Bj{\o}rn-Mortensen and {Graff Jensen}, Sidse and {Sloth Andersen}, Ellen and Pernille Ravn",

note = "Funding Information: This work was supported by Gilead Sciences, Inc. under Grant 04675. Publisher Copyright: {\textcopyright} 2021 Society for Scandinavian Journal of Infectious Diseases.",

year = "2021",

doi = "10.1080/23744235.2020.1865562",

language = "English",

volume = "53",

pages = "196--200",

journal = "Infectious Diseases",

issn = "2374-4235",

publisher = "Taylor & Francis",

number = "3",

}

RIS

TY - JOUR

T1 - Prevalence of hepatitis B and C at a major tuberculosis centre in Denmark

AU - Jørgensen, Anja

AU - Bjørn-Mortensen, Karen

AU - Graff Jensen, Sidse

AU - Sloth Andersen, Ellen

AU - Ravn, Pernille

PY - 2021

Y1 - 2021

N2 - Background: Denmark is a low-prevalence country for tuberculosis (TB), hepatitis B (HBV), and hepatitis C (HCV) but the three diseases have similar sociodemographic risk factors. We estimated the prevalence and possible risk factors of HBV and HCV among TB-patients in a large TB clinic in Denmark. Methods: All patients starting anti-TB-treatment at Copenhagen University Hospital, Herlev-Gentofte from April 1st 2018 through June 1st 2019 were included. Results from HBV and HCV testing as well as sociodemographic information were collected. Risk factor analyses were carried out using descriptive statistics. Results: Of 82 patients tested for HBV, one (1.2%) had chronic HBV and 16 (19.5%) had serocleared HBV. Of 91 patients tested for HCV, three (3.3%) had chronic HCV and one (1.1%) had serocleared HCV. Country of origin other than Denmark was significantly associated with HBV-seropositivity among TB-patients, particularly patients from Greenland, Asia, Africa and Eastern Europe. No other significantly associated risk factors were found. Conclusion: The prevalences of chronic and prior HBV and HCV among TB-patients were lower compared to studies in TB high endemic areas but higher than those found in the Danish background population. We calculated the number needed to test to find one patient with HBV ranged between 27 and 83 and we suggest continuing screening of chronic HBV and HCV in TB-patients in Denmark.

AB - Background: Denmark is a low-prevalence country for tuberculosis (TB), hepatitis B (HBV), and hepatitis C (HCV) but the three diseases have similar sociodemographic risk factors. We estimated the prevalence and possible risk factors of HBV and HCV among TB-patients in a large TB clinic in Denmark. Methods: All patients starting anti-TB-treatment at Copenhagen University Hospital, Herlev-Gentofte from April 1st 2018 through June 1st 2019 were included. Results from HBV and HCV testing as well as sociodemographic information were collected. Risk factor analyses were carried out using descriptive statistics. Results: Of 82 patients tested for HBV, one (1.2%) had chronic HBV and 16 (19.5%) had serocleared HBV. Of 91 patients tested for HCV, three (3.3%) had chronic HCV and one (1.1%) had serocleared HCV. Country of origin other than Denmark was significantly associated with HBV-seropositivity among TB-patients, particularly patients from Greenland, Asia, Africa and Eastern Europe. No other significantly associated risk factors were found. Conclusion: The prevalences of chronic and prior HBV and HCV among TB-patients were lower compared to studies in TB high endemic areas but higher than those found in the Danish background population. We calculated the number needed to test to find one patient with HBV ranged between 27 and 83 and we suggest continuing screening of chronic HBV and HCV in TB-patients in Denmark.

KW - Denmark

KW - hepatitis B

KW - hepatitis C

KW - risk factors

KW - Tuberculosis

U2 - 10.1080/23744235.2020.1865562

DO - 10.1080/23744235.2020.1865562

M3 - Journal article

C2 - 33406978

AN - SCOPUS:85099314678

VL - 53

SP - 196

EP - 200

JO - Infectious Diseases

JF - Infectious Diseases

SN - 2374-4235

IS - 3

ER -

ID: 302162232