TY - JOUR

T1 - Plasmid-encoded resistance to macrolides and lincosamides in Staphylococcus hyicus

AU - Schwarz, S

AU - Wegener, Henrik Caspar

AU - Blobel, H

PY - 1990/12

Y1 - 1990/12

N2 - A small plasmid of 2.35 kb, isolated from a porcine Staphylococcus hyicus-culture, was found to be responsible for constitutive resistance to macrolide/lincosamide antibiotics. This plasmid-encoded property could be established by interspecific transformation experiments. The plasmid from porcine Staph. hyicus was designated as pSE2. It differed on the basis of its restriction map from the macrolid/lincosamid resistance (MLR-)-plasmids of other staphylococcal species from infections of humans. Furthermore, the pSE2 plasmid encoded two proteins of approximately 20.5 and 30 kDa.

AB - A small plasmid of 2.35 kb, isolated from a porcine Staphylococcus hyicus-culture, was found to be responsible for constitutive resistance to macrolide/lincosamide antibiotics. This plasmid-encoded property could be established by interspecific transformation experiments. The plasmid from porcine Staph. hyicus was designated as pSE2. It differed on the basis of its restriction map from the macrolid/lincosamid resistance (MLR-)-plasmids of other staphylococcal species from infections of humans. Furthermore, the pSE2 plasmid encoded two proteins of approximately 20.5 and 30 kDa.

KW - Animals

KW - Anti-Bacterial Agents

KW - Bacterial Proteins

KW - Clindamycin

KW - DNA, Bacterial

KW - Drug Resistance, Microbial

KW - Electrophoresis, Agar Gel

KW - Epidermitis, Exudative, of Swine

KW - Erythromycin

KW - Lincomycin

KW - Lincosamides

KW - Macrolides

KW - Oleandomycin

KW - R Factors

KW - Restriction Mapping

KW - Staphylococcus

KW - Swine

KW - Journal Article

M3 - Journal article

C2 - 2286583

VL - 69

SP - 845

EP - 849

JO - Journal of Applied Bacteriology

JF - Journal of Applied Bacteriology

SN - 0021-8847

IS - 6

ER -