Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain)
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Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain). / López, Víctor; Jäger, Anna Katharina; Akerreta, Silvia; Cavero, Rita Yolanda; Calvo, Maria Isabel.
I: Journal of Ethnopharmacology, Bind 134, Nr. 3, 12.04.2011, s. 1014-1017.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain)
AU - López, Víctor
AU - Jäger, Anna Katharina
AU - Akerreta, Silvia
AU - Cavero, Rita Yolanda
AU - Calvo, Maria Isabel
N1 - Keywords: Anagallis arvensis, Anagallis foemina, Primulaceae, traditional medicine, antimicrobial, anti-inflammatory
PY - 2011/4/12
Y1 - 2011/4/12
N2 - ETHNOPHARMACOLOGICAL RELEVANCE: : Anagallis arvensis and Anagallis foemina are traditionally used in Navarra (Spain) for dermatological purposes regarding wound healing properties. In some cases they are also used to threat internal infections although they are known to be toxic at high doses. AIM OF STUDY: : Due to lack of studies, we decided to evaluate the potential of the plants as wound healing remedies measuring antimicrobial and anti-inflammatory properties using in vitro procedures. MATERIALS AND METHODS: Antimicrobial effects were studied against four bacteria and one fungus. Anti-inflammatory properties were measured in terms of COX-1 and -2 inhibition as well as superoxide radical scavenging capacity. RESULTS: Both species exerted antimicrobial and anti-inflammatory effects. The methanolic extract obtained from Anagallis arvensis seemed to produce the highest inhibition in Candida albicans (MIC=0.31mg/ml). Inhibition of COX-1 and -2 was also stronger for methanolic extracts whereas aqueous were revealed as better free radical scavengers. CONCLUSIONS: The study reveals that both species posses antimicrobial and anti-inflammatory activities related to their ethnomedicinal uses.
AB - ETHNOPHARMACOLOGICAL RELEVANCE: : Anagallis arvensis and Anagallis foemina are traditionally used in Navarra (Spain) for dermatological purposes regarding wound healing properties. In some cases they are also used to threat internal infections although they are known to be toxic at high doses. AIM OF STUDY: : Due to lack of studies, we decided to evaluate the potential of the plants as wound healing remedies measuring antimicrobial and anti-inflammatory properties using in vitro procedures. MATERIALS AND METHODS: Antimicrobial effects were studied against four bacteria and one fungus. Anti-inflammatory properties were measured in terms of COX-1 and -2 inhibition as well as superoxide radical scavenging capacity. RESULTS: Both species exerted antimicrobial and anti-inflammatory effects. The methanolic extract obtained from Anagallis arvensis seemed to produce the highest inhibition in Candida albicans (MIC=0.31mg/ml). Inhibition of COX-1 and -2 was also stronger for methanolic extracts whereas aqueous were revealed as better free radical scavengers. CONCLUSIONS: The study reveals that both species posses antimicrobial and anti-inflammatory activities related to their ethnomedicinal uses.
KW - Former Faculty of Pharmaceutical Sciences
U2 - 10.1016/j.jep.2010.12.036
DO - 10.1016/j.jep.2010.12.036
M3 - Journal article
C2 - 21237261
VL - 134
SP - 1014
EP - 1017
JO - Journal of Ethnopharmacology
JF - Journal of Ethnopharmacology
SN - 0378-8741
IS - 3
ER -
ID: 32661299