Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders : Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy. / Eskildsen, Anita; Reinholt, Nina; van Bronswijk, Suzanne; Brund, René B.K.; Christensen, Anne Bryde; Hvenegaard, Morten; Arendt, Mikkel; Alrø, Anja; Poulsen, Stig; Rosenberg, Nicole K.; Huibers, Marcus J.H.; Arnfred, Sidse.

I: Cognitive Therapy and Research, Bind 44, 2020, s. 988–1001.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Eskildsen, A, Reinholt, N, van Bronswijk, S, Brund, RBK, Christensen, AB, Hvenegaard, M, Arendt, M, Alrø, A, Poulsen, S, Rosenberg, NK, Huibers, MJH & Arnfred, S 2020, 'Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy', Cognitive Therapy and Research, bind 44, s. 988–1001. https://doi.org/10.1007/s10608-020-10116-1

APA

Eskildsen, A., Reinholt, N., van Bronswijk, S., Brund, R. B. K., Christensen, A. B., Hvenegaard, M., Arendt, M., Alrø, A., Poulsen, S., Rosenberg, N. K., Huibers, M. J. H., & Arnfred, S. (2020). Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy. Cognitive Therapy and Research, 44, 988–1001. https://doi.org/10.1007/s10608-020-10116-1

Vancouver

Eskildsen A, Reinholt N, van Bronswijk S, Brund RBK, Christensen AB, Hvenegaard M o.a. Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy. Cognitive Therapy and Research. 2020;44:988–1001. https://doi.org/10.1007/s10608-020-10116-1

Author

Eskildsen, Anita ; Reinholt, Nina ; van Bronswijk, Suzanne ; Brund, René B.K. ; Christensen, Anne Bryde ; Hvenegaard, Morten ; Arendt, Mikkel ; Alrø, Anja ; Poulsen, Stig ; Rosenberg, Nicole K. ; Huibers, Marcus J.H. ; Arnfred, Sidse. / Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders : Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy. I: Cognitive Therapy and Research. 2020 ; Bind 44. s. 988–1001.

Bibtex

@article{10ee2afb2c604131bf6c4983c94f473d,
title = "Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy",
abstract = "Background: Only about half of all patients with anxiety disorders or major depression respond to cognitive behaviour therapy (CBT), even though this is an evidence-based treatment. Personalized treatment offers an approach to increase the number of patients who respond to therapy. The aim of this study was to examine predictors and moderators of (differential) treatment outcomes in transdiagnostic versus diagnosis-specific group CBT. Methods: A sample of 291 patients from three different mental health clinics in Denmark was randomized to either transdiagnostic or diagnosis-specific group CBT. The study outcome was the regression slope of the individual patient's repeated scores on the WHO-5 Well-being Index. Pre-treatment variables were identified as moderators or predictors through a two-step variable selection approach. Results: While the two-step approach failed to identify any moderators, four predictors were found: level of positive affect, duration of disorder, the detachment personality trait, and the coping strategy of cognitive reappraisal. A prognostic index was constructed, but did not seem to be robust across treatment sites. Conclusions: Our findings give insufficient evidence to support a recommendation of either transdiagnostic or diagnosis-specific CBT for a given patient or to predict the response to the applied group therapies.",
keywords = "Anxiety disorders, Cognitive behaviour therapy, Major depression, Precision medicine, Unified protocol",
author = "Anita Eskildsen and Nina Reinholt and {van Bronswijk}, Suzanne and Brund, {Ren{\'e} B.K.} and Christensen, {Anne Bryde} and Morten Hvenegaard and Mikkel Arendt and Anja Alr{\o} and Stig Poulsen and Rosenberg, {Nicole K.} and Huibers, {Marcus J.H.} and Sidse Arnfred",
year = "2020",
doi = "10.1007/s10608-020-10116-1",
language = "English",
volume = "44",
pages = "988–1001",
journal = "Cognitive Therapy and Research",
issn = "0147-5916",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders

T2 - Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy

AU - Eskildsen, Anita

AU - Reinholt, Nina

AU - van Bronswijk, Suzanne

AU - Brund, René B.K.

AU - Christensen, Anne Bryde

AU - Hvenegaard, Morten

AU - Arendt, Mikkel

AU - Alrø, Anja

AU - Poulsen, Stig

AU - Rosenberg, Nicole K.

AU - Huibers, Marcus J.H.

AU - Arnfred, Sidse

PY - 2020

Y1 - 2020

N2 - Background: Only about half of all patients with anxiety disorders or major depression respond to cognitive behaviour therapy (CBT), even though this is an evidence-based treatment. Personalized treatment offers an approach to increase the number of patients who respond to therapy. The aim of this study was to examine predictors and moderators of (differential) treatment outcomes in transdiagnostic versus diagnosis-specific group CBT. Methods: A sample of 291 patients from three different mental health clinics in Denmark was randomized to either transdiagnostic or diagnosis-specific group CBT. The study outcome was the regression slope of the individual patient's repeated scores on the WHO-5 Well-being Index. Pre-treatment variables were identified as moderators or predictors through a two-step variable selection approach. Results: While the two-step approach failed to identify any moderators, four predictors were found: level of positive affect, duration of disorder, the detachment personality trait, and the coping strategy of cognitive reappraisal. A prognostic index was constructed, but did not seem to be robust across treatment sites. Conclusions: Our findings give insufficient evidence to support a recommendation of either transdiagnostic or diagnosis-specific CBT for a given patient or to predict the response to the applied group therapies.

AB - Background: Only about half of all patients with anxiety disorders or major depression respond to cognitive behaviour therapy (CBT), even though this is an evidence-based treatment. Personalized treatment offers an approach to increase the number of patients who respond to therapy. The aim of this study was to examine predictors and moderators of (differential) treatment outcomes in transdiagnostic versus diagnosis-specific group CBT. Methods: A sample of 291 patients from three different mental health clinics in Denmark was randomized to either transdiagnostic or diagnosis-specific group CBT. The study outcome was the regression slope of the individual patient's repeated scores on the WHO-5 Well-being Index. Pre-treatment variables were identified as moderators or predictors through a two-step variable selection approach. Results: While the two-step approach failed to identify any moderators, four predictors were found: level of positive affect, duration of disorder, the detachment personality trait, and the coping strategy of cognitive reappraisal. A prognostic index was constructed, but did not seem to be robust across treatment sites. Conclusions: Our findings give insufficient evidence to support a recommendation of either transdiagnostic or diagnosis-specific CBT for a given patient or to predict the response to the applied group therapies.

KW - Anxiety disorders

KW - Cognitive behaviour therapy

KW - Major depression

KW - Precision medicine

KW - Unified protocol

U2 - 10.1007/s10608-020-10116-1

DO - 10.1007/s10608-020-10116-1

M3 - Journal article

AN - SCOPUS:85085339900

VL - 44

SP - 988

EP - 1001

JO - Cognitive Therapy and Research

JF - Cognitive Therapy and Research

SN - 0147-5916

ER -

ID: 243151635