PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Standard

PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity. / Janaszewska, Anna; Studzian, Maciej; Petersen, Johannes Fabritius; Ficker, Mario; Christensen, Jørn Bolstad; Klajnert-Maculewicz, Barbara.

I: Nanomedicine: Nanotechnology, Biology and Medicine, Bind 11, Nr. 2, 2015, s. 409-411.

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Harvard

Janaszewska, A, Studzian, M, Petersen, JF, Ficker, M, Christensen, JB & Klajnert-Maculewicz, B 2015, 'PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity', Nanomedicine: Nanotechnology, Biology and Medicine, bind 11, nr. 2, s. 409-411. https://doi.org/10.1016/j.nano.2014.09.011

APA

Janaszewska, A., Studzian, M., Petersen, J. F., Ficker, M., Christensen, J. B., & Klajnert-Maculewicz, B. (2015). PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity. Nanomedicine: Nanotechnology, Biology and Medicine, 11(2), 409-411. https://doi.org/10.1016/j.nano.2014.09.011

Vancouver

Janaszewska A, Studzian M, Petersen JF, Ficker M, Christensen JB, Klajnert-Maculewicz B. PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity. Nanomedicine: Nanotechnology, Biology and Medicine. 2015;11(2):409-411. https://doi.org/10.1016/j.nano.2014.09.011

Author

Janaszewska, Anna ; Studzian, Maciej ; Petersen, Johannes Fabritius ; Ficker, Mario ; Christensen, Jørn Bolstad ; Klajnert-Maculewicz, Barbara. / PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity. I: Nanomedicine: Nanotechnology, Biology and Medicine. 2015 ; Bind 11, Nr. 2. s. 409-411.

Bibtex

@article{3b088a41d96245e5b30148ab65d8033f,

title = "PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity",

abstract = "Cytotoxicity of cationic amino-terminated PAMAM dendrimer and modified PAMAM-pyrrolidone dendrimer was compared. LDH assay and cell visualization technique were employed. Mouse embryonic hippocampal cells (mHippoE-18) were used. The experiments were performed in FBS-deprived medium. Pyrrolidone-modification significantly diminished toxicity of PAMAM dendrimer. The absence of FBS did not reveal significant impact on the toxic effect. Results from LDH assay and MTT test were in good consistency. Low cytotoxicity of PAMAM-pyrrolidone dendrimer increases reliability of the results showing a small impact of this dendrimer on cell viability.",

author = "Anna Janaszewska and Maciej Studzian and Petersen, {Johannes Fabritius} and Mario Ficker and Christensen, {J{\o}rn Bolstad} and Barbara Klajnert-Maculewicz",

year = "2015",

doi = "10.1016/j.nano.2014.09.011",

language = "English",

volume = "11",

pages = "409--411",

journal = "Nanomedicine: Nanotechnology, Biology and Medicine",

issn = "1549-9634",

publisher = "Elsevier",

number = "2",

}

RIS

TY - JOUR

T1 - PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity

AU - Janaszewska, Anna

AU - Studzian, Maciej

AU - Petersen, Johannes Fabritius

AU - Ficker, Mario

AU - Christensen, Jørn Bolstad

AU - Klajnert-Maculewicz, Barbara

PY - 2015

Y1 - 2015

N2 - Cytotoxicity of cationic amino-terminated PAMAM dendrimer and modified PAMAM-pyrrolidone dendrimer was compared. LDH assay and cell visualization technique were employed. Mouse embryonic hippocampal cells (mHippoE-18) were used. The experiments were performed in FBS-deprived medium. Pyrrolidone-modification significantly diminished toxicity of PAMAM dendrimer. The absence of FBS did not reveal significant impact on the toxic effect. Results from LDH assay and MTT test were in good consistency. Low cytotoxicity of PAMAM-pyrrolidone dendrimer increases reliability of the results showing a small impact of this dendrimer on cell viability.

AB - Cytotoxicity of cationic amino-terminated PAMAM dendrimer and modified PAMAM-pyrrolidone dendrimer was compared. LDH assay and cell visualization technique were employed. Mouse embryonic hippocampal cells (mHippoE-18) were used. The experiments were performed in FBS-deprived medium. Pyrrolidone-modification significantly diminished toxicity of PAMAM dendrimer. The absence of FBS did not reveal significant impact on the toxic effect. Results from LDH assay and MTT test were in good consistency. Low cytotoxicity of PAMAM-pyrrolidone dendrimer increases reliability of the results showing a small impact of this dendrimer on cell viability.

U2 - 10.1016/j.nano.2014.09.011

DO - 10.1016/j.nano.2014.09.011

M3 - Letter

C2 - 25461280

VL - 11

SP - 409

EP - 411

JO - Nanomedicine: Nanotechnology, Biology and Medicine

JF - Nanomedicine: Nanotechnology, Biology and Medicine

SN - 1549-9634

IS - 2

ER -

ID: 131612390