Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity

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Standard

Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity. / Lee, Blaire; Sosnovtseva, Olga; Sorensen, Charlotte M.; Postnov, Dmitry D.

I: Biomedical Optics Express, Bind 13, Nr. 4, 2022, s. 2312-2322.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lee, B, Sosnovtseva, O, Sorensen, CM & Postnov, DD 2022, 'Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity', Biomedical Optics Express, bind 13, nr. 4, s. 2312-2322. https://doi.org/10.1364/BOE.451014

APA

Lee, B., Sosnovtseva, O., Sorensen, C. M., & Postnov, D. D. (2022). Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity. Biomedical Optics Express, 13(4), 2312-2322. https://doi.org/10.1364/BOE.451014

Vancouver

Lee B, Sosnovtseva O, Sorensen CM, Postnov DD. Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity. Biomedical Optics Express. 2022;13(4):2312-2322. https://doi.org/10.1364/BOE.451014

Author

Lee, Blaire ; Sosnovtseva, Olga ; Sorensen, Charlotte M. ; Postnov, Dmitry D. / Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity. I: Biomedical Optics Express. 2022 ; Bind 13, Nr. 4. s. 2312-2322.

Bibtex

@article{336f6b1b37ca48218ce9e5a4a5b1d5b1,

title = "Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity",

abstract = "Laser speckle contrast imaging is a robust and versatile blood flow imaging tool in basic and clinical research for its relatively simple construction and ease of customization. One of its key features is the scalability of the imaged field of view. With minimal changes to the system or analysis, laser speckle contrast imaging allows for high-resolution blood flow imaging through cranial windows or low-resolution perfusion visualization of perfusion over large areas, e.g. in human skin. We further utilize this feature and introduce a multi-scale laser speckle contrast imaging system, which we apply to study vasoreactivity in renal microcirculation. We combine high resolution (small field of view) to segment blood flow in individual vessels with low resolution (large field of view) to monitor global blood flow changes across the renal surface. Furthermore, we compare their performance when analyzing blood flow dynamics potentially associated with a single nephron and show that the previously published approaches, based on low-zoom imaging alone, provide inaccurate results in such applications. ",

author = "Blaire Lee and Olga Sosnovtseva and Sorensen, {Charlotte M.} and Postnov, {Dmitry D.}",

note = "Publisher Copyright: {\textcopyright} 2022 Optica Publishing Group.",

year = "2022",

doi = "10.1364/BOE.451014",

language = "English",

volume = "13",

pages = "2312--2322",

journal = "Biomedical Optics Express",

issn = "2156-7085",

publisher = "Optical Society of America",

number = "4",

}

RIS

TY - JOUR

T1 - Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity

AU - Lee, Blaire

AU - Sosnovtseva, Olga

AU - Sorensen, Charlotte M.

AU - Postnov, Dmitry D.

PY - 2022

Y1 - 2022

N2 - Laser speckle contrast imaging is a robust and versatile blood flow imaging tool in basic and clinical research for its relatively simple construction and ease of customization. One of its key features is the scalability of the imaged field of view. With minimal changes to the system or analysis, laser speckle contrast imaging allows for high-resolution blood flow imaging through cranial windows or low-resolution perfusion visualization of perfusion over large areas, e.g. in human skin. We further utilize this feature and introduce a multi-scale laser speckle contrast imaging system, which we apply to study vasoreactivity in renal microcirculation. We combine high resolution (small field of view) to segment blood flow in individual vessels with low resolution (large field of view) to monitor global blood flow changes across the renal surface. Furthermore, we compare their performance when analyzing blood flow dynamics potentially associated with a single nephron and show that the previously published approaches, based on low-zoom imaging alone, provide inaccurate results in such applications.

AB - Laser speckle contrast imaging is a robust and versatile blood flow imaging tool in basic and clinical research for its relatively simple construction and ease of customization. One of its key features is the scalability of the imaged field of view. With minimal changes to the system or analysis, laser speckle contrast imaging allows for high-resolution blood flow imaging through cranial windows or low-resolution perfusion visualization of perfusion over large areas, e.g. in human skin. We further utilize this feature and introduce a multi-scale laser speckle contrast imaging system, which we apply to study vasoreactivity in renal microcirculation. We combine high resolution (small field of view) to segment blood flow in individual vessels with low resolution (large field of view) to monitor global blood flow changes across the renal surface. Furthermore, we compare their performance when analyzing blood flow dynamics potentially associated with a single nephron and show that the previously published approaches, based on low-zoom imaging alone, provide inaccurate results in such applications.

U2 - 10.1364/BOE.451014

DO - 10.1364/BOE.451014

M3 - Journal article

C2 - 35519248

AN - SCOPUS:85126932626

VL - 13

SP - 2312

EP - 2322

JO - Biomedical Optics Express

JF - Biomedical Optics Express

SN - 2156-7085

IS - 4

ER -

ID: 302555864