Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment

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Standard

Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment. / Saunte, Ditte M.L.; Gaitanis, George; Hay, Roderick James.

I: Frontiers in Cellular and Infection Microbiology, Bind 10, 112, 03.2020.

Publikation: Bidrag til tidsskriftReviewfagfællebedømt

Harvard

Saunte, DML, Gaitanis, G & Hay, RJ 2020, 'Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment', Frontiers in Cellular and Infection Microbiology, bind 10, 112. https://doi.org/10.3389/fcimb.2020.00112

APA

Saunte, D. M. L., Gaitanis, G., & Hay, R. J. (2020). Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment. Frontiers in Cellular and Infection Microbiology, 10, [112]. https://doi.org/10.3389/fcimb.2020.00112

Vancouver

Saunte DML, Gaitanis G, Hay RJ. Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment. Frontiers in Cellular and Infection Microbiology. 2020 mar.;10. 112. https://doi.org/10.3389/fcimb.2020.00112

Author

Saunte, Ditte M.L. ; Gaitanis, George ; Hay, Roderick James. / Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment. I: Frontiers in Cellular and Infection Microbiology. 2020 ; Bind 10.

Bibtex

@article{5ada20e23bf64724b77ccb5bfb758c12,
title = "Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment",
abstract = "Yeasts of the genus, Malassezia, formerly known as Pityrosporum, are lipophilic yeasts, which are a part of the normal skin flora (microbiome). Malassezia colonize the human skin after birth and must therefore, as commensals, be normally tolerated by the human immune system. The Malassezia yeasts also have a pathogenic potential where they can, under appropriate conditions, invade the stratum corneum and interact with the host immune system, both directly but also through chemical mediators. The species distribution on the skin and the pathogenetic potential of the yeast varies between different Malassezia related diseases such as head and neck dermatitis, seborrheic dermatitis, pityriasis versicolor, and Malassezia folliculitis. The diagnostic methods used to confirm the presence of Malassezia yeasts include direct microcopy, culture based methods (often a combination of morphological features of the isolate combined with biochemical test), molecular based methods such as Polymerase Chain Reaction techniques, and Matrix Assisted Laser Desorption/Ionization—Time Of Flight mass spectrometry and the chemical imprint method Raman spectroscopy. Skin diseases caused by Malassezia are usually treated with antifungal therapy and if there are associated inflammatory skin mechanisms this is often supplemented by anti-inflammatory therapy. The aim of this paper is to provide an overview of Malassezia related skin disease, diagnostic methods and treatment options.",
keywords = "folliculitis, head and neck dermatitis, Malassezia, pityriasis versicolor, seborrheic dermatitis",
author = "Saunte, {Ditte M.L.} and George Gaitanis and Hay, {Roderick James}",
year = "2020",
month = mar,
doi = "10.3389/fcimb.2020.00112",
language = "English",
volume = "10",
journal = "Frontiers in Cellular and Infection Microbiology",
issn = "2235-2988",
publisher = "Frontiers Media S.A.",

}

RIS

TY - JOUR

T1 - Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment

AU - Saunte, Ditte M.L.

AU - Gaitanis, George

AU - Hay, Roderick James

PY - 2020/3

Y1 - 2020/3

N2 - Yeasts of the genus, Malassezia, formerly known as Pityrosporum, are lipophilic yeasts, which are a part of the normal skin flora (microbiome). Malassezia colonize the human skin after birth and must therefore, as commensals, be normally tolerated by the human immune system. The Malassezia yeasts also have a pathogenic potential where they can, under appropriate conditions, invade the stratum corneum and interact with the host immune system, both directly but also through chemical mediators. The species distribution on the skin and the pathogenetic potential of the yeast varies between different Malassezia related diseases such as head and neck dermatitis, seborrheic dermatitis, pityriasis versicolor, and Malassezia folliculitis. The diagnostic methods used to confirm the presence of Malassezia yeasts include direct microcopy, culture based methods (often a combination of morphological features of the isolate combined with biochemical test), molecular based methods such as Polymerase Chain Reaction techniques, and Matrix Assisted Laser Desorption/Ionization—Time Of Flight mass spectrometry and the chemical imprint method Raman spectroscopy. Skin diseases caused by Malassezia are usually treated with antifungal therapy and if there are associated inflammatory skin mechanisms this is often supplemented by anti-inflammatory therapy. The aim of this paper is to provide an overview of Malassezia related skin disease, diagnostic methods and treatment options.

AB - Yeasts of the genus, Malassezia, formerly known as Pityrosporum, are lipophilic yeasts, which are a part of the normal skin flora (microbiome). Malassezia colonize the human skin after birth and must therefore, as commensals, be normally tolerated by the human immune system. The Malassezia yeasts also have a pathogenic potential where they can, under appropriate conditions, invade the stratum corneum and interact with the host immune system, both directly but also through chemical mediators. The species distribution on the skin and the pathogenetic potential of the yeast varies between different Malassezia related diseases such as head and neck dermatitis, seborrheic dermatitis, pityriasis versicolor, and Malassezia folliculitis. The diagnostic methods used to confirm the presence of Malassezia yeasts include direct microcopy, culture based methods (often a combination of morphological features of the isolate combined with biochemical test), molecular based methods such as Polymerase Chain Reaction techniques, and Matrix Assisted Laser Desorption/Ionization—Time Of Flight mass spectrometry and the chemical imprint method Raman spectroscopy. Skin diseases caused by Malassezia are usually treated with antifungal therapy and if there are associated inflammatory skin mechanisms this is often supplemented by anti-inflammatory therapy. The aim of this paper is to provide an overview of Malassezia related skin disease, diagnostic methods and treatment options.

KW - folliculitis

KW - head and neck dermatitis

KW - Malassezia

KW - pityriasis versicolor

KW - seborrheic dermatitis

U2 - 10.3389/fcimb.2020.00112

DO - 10.3389/fcimb.2020.00112

M3 - Review

C2 - 32266163

AN - SCOPUS:85083044477

VL - 10

JO - Frontiers in Cellular and Infection Microbiology

JF - Frontiers in Cellular and Infection Microbiology

SN - 2235-2988

M1 - 112

ER -

ID: 243153267