Human bronchial artery blood flow after lung Tx with direct bronchial artery revascularization
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The inaccuracy of measuring human bronchial artery blood flow has previously been considerable. En bloc double-lung transplantation with bronchial artery revascularization (BAR) using a single conduit offers the unique opportunity of direct measurement of the total bronchial artery blood flow. In eight en bloc double-lung-transplanted patients with complete BAR, the basal blood flow was measured by using a 0.014-in. Doppler guide wire and arteriography. The average peak velocity in the conduit was 12-73 cm/s [±2.1 (SD) cm/s], and the conduit diameter was 1.7-3.1 mm [±0.10 (SD) mm], giving individual basal flow values between 19 and 67 ml/min [±5 (SD) ml/min], or 0.2-1.9% of estimated cardiac output. In three patients basal measurements were followed by injection of nitroglycerin and verapamil into the conduit. This increased the bronchial artery flow to 121-262% of basal values (31-89 ml/min). The measured values appear more physiologically plausible than previous bronchial artery blood flow measurements in humans.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Applied Physiology |
Vol/bind | 87 |
Udgave nummer | 3 |
Sider (fra-til) | 1234-1239 |
Antal sider | 6 |
ISSN | 8750-7587 |
DOI | |
Status | Udgivet - sep. 1999 |
ID: 308767645