Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain. / Fordyce, Sarah Louise; Bragstad, Karoline; Pedersen, Svend Stenvang; Jensen, Thøger G.; Gahrn-Hansen, Bente; Daniels, Rod; Hay, Alan; Kampmann, Marie-Louise; Bruhn, Christian Anders Wathne; Moreno Mayar, José Victor; Avila Arcos, Maria del Carmen; Gilbert, Tom; Nielsen, Lars P.

I: Virology Journal, Bind 10, 116, 2013.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Fordyce, SL, Bragstad, K, Pedersen, SS, Jensen, TG, Gahrn-Hansen, B, Daniels, R, Hay, A, Kampmann, M-L, Bruhn, CAW, Moreno Mayar, JV, Avila Arcos, MDC, Gilbert, T & Nielsen, LP 2013, 'Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain', Virology Journal, bind 10, 116. https://doi.org/10.1186/1743-422X-10-116

APA

Fordyce, S. L., Bragstad, K., Pedersen, S. S., Jensen, T. G., Gahrn-Hansen, B., Daniels, R., Hay, A., Kampmann, M-L., Bruhn, C. A. W., Moreno Mayar, J. V., Avila Arcos, M. D. C., Gilbert, T., & Nielsen, L. P. (2013). Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain. Virology Journal, 10, [116]. https://doi.org/10.1186/1743-422X-10-116

Vancouver

Fordyce SL, Bragstad K, Pedersen SS, Jensen TG, Gahrn-Hansen B, Daniels R o.a. Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain. Virology Journal. 2013;10. 116. https://doi.org/10.1186/1743-422X-10-116

Author

Fordyce, Sarah Louise ; Bragstad, Karoline ; Pedersen, Svend Stenvang ; Jensen, Thøger G. ; Gahrn-Hansen, Bente ; Daniels, Rod ; Hay, Alan ; Kampmann, Marie-Louise ; Bruhn, Christian Anders Wathne ; Moreno Mayar, José Victor ; Avila Arcos, Maria del Carmen ; Gilbert, Tom ; Nielsen, Lars P. / Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain. I: Virology Journal. 2013 ; Bind 10.

Bibtex

@article{2aa3764bbbc548a79b24253814ddb7be,
title = "Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain",
abstract = "Influenza viruses such as swine-origin influenza A(H1N1) virus (A(H1N1)pdm09) generate genetic diversity due to the high error rate of their RNA polymerase, often resulting in mixed genotype populations (intra-host variants) within a single infection. This variation helps influenza to rapidly respond to selection pressures, such as those imposed by the immunological host response and antiviral therapy. We have applied deep sequencing to characterize influenza intra-host variation in a transmission chain consisting of three cases due to oseltamivir-sensitive viruses, and one derived oseltamivir-resistant case.",
author = "Fordyce, {Sarah Louise} and Karoline Bragstad and Pedersen, {Svend Stenvang} and Jensen, {Th{\o}ger G.} and Bente Gahrn-Hansen and Rod Daniels and Alan Hay and Marie-Louise Kampmann and Bruhn, {Christian Anders Wathne} and {Moreno Mayar}, {Jos{\'e} Victor} and {Avila Arcos}, {Maria del Carmen} and Tom Gilbert and Nielsen, {Lars P.}",
year = "2013",
doi = "10.1186/1743-422X-10-116",
language = "English",
volume = "10",
journal = "Virology Journal",
issn = "1743-422X",
publisher = "BioMed Central",

}

RIS

TY - JOUR

T1 - Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain

AU - Fordyce, Sarah Louise

AU - Bragstad, Karoline

AU - Pedersen, Svend Stenvang

AU - Jensen, Thøger G.

AU - Gahrn-Hansen, Bente

AU - Daniels, Rod

AU - Hay, Alan

AU - Kampmann, Marie-Louise

AU - Bruhn, Christian Anders Wathne

AU - Moreno Mayar, José Victor

AU - Avila Arcos, Maria del Carmen

AU - Gilbert, Tom

AU - Nielsen, Lars P.

PY - 2013

Y1 - 2013

N2 - Influenza viruses such as swine-origin influenza A(H1N1) virus (A(H1N1)pdm09) generate genetic diversity due to the high error rate of their RNA polymerase, often resulting in mixed genotype populations (intra-host variants) within a single infection. This variation helps influenza to rapidly respond to selection pressures, such as those imposed by the immunological host response and antiviral therapy. We have applied deep sequencing to characterize influenza intra-host variation in a transmission chain consisting of three cases due to oseltamivir-sensitive viruses, and one derived oseltamivir-resistant case.

AB - Influenza viruses such as swine-origin influenza A(H1N1) virus (A(H1N1)pdm09) generate genetic diversity due to the high error rate of their RNA polymerase, often resulting in mixed genotype populations (intra-host variants) within a single infection. This variation helps influenza to rapidly respond to selection pressures, such as those imposed by the immunological host response and antiviral therapy. We have applied deep sequencing to characterize influenza intra-host variation in a transmission chain consisting of three cases due to oseltamivir-sensitive viruses, and one derived oseltamivir-resistant case.

U2 - 10.1186/1743-422X-10-116

DO - 10.1186/1743-422X-10-116

M3 - Journal article

C2 - 23587185

VL - 10

JO - Virology Journal

JF - Virology Journal

SN - 1743-422X

M1 - 116

ER -

ID: 46090172