Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins

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Standard

Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins. / Geczy, Reka; Christensen, Niels Johan; Rasmussen, Kim K; Kálomista, Ildikó; Tiwari, Manish K; Shah, Pratik; Yang, Seong Wook; Bjerrum, Morten J; Thulstrup, Peter Waaben.

I: Angewandte Chemie, Int. Ed., Bind 59, Nr. 37, 2020, s. 16091-16097.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Geczy, R, Christensen, NJ, Rasmussen, KK, Kálomista, I, Tiwari, MK, Shah, P, Yang, SW, Bjerrum, MJ & Thulstrup, PW 2020, 'Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins', Angewandte Chemie, Int. Ed., bind 59, nr. 37, s. 16091-16097. https://doi.org/10.1002/anie.202005102

APA

Geczy, R., Christensen, N. J., Rasmussen, K. K., Kálomista, I., Tiwari, M. K., Shah, P., Yang, S. W., Bjerrum, M. J., & Thulstrup, P. W. (2020). Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins. Angewandte Chemie, Int. Ed., 59(37), 16091-16097. https://doi.org/10.1002/anie.202005102

Vancouver

Geczy R, Christensen NJ, Rasmussen KK, Kálomista I, Tiwari MK, Shah P o.a. Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins. Angewandte Chemie, Int. Ed. 2020;59(37):16091-16097. https://doi.org/10.1002/anie.202005102

Author

Geczy, Reka ; Christensen, Niels Johan ; Rasmussen, Kim K ; Kálomista, Ildikó ; Tiwari, Manish K ; Shah, Pratik ; Yang, Seong Wook ; Bjerrum, Morten J ; Thulstrup, Peter Waaben. / Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins. I: Angewandte Chemie, Int. Ed. 2020 ; Bind 59, Nr. 37. s. 16091-16097.

Bibtex

@article{0340c69afc7e491e8c4263c53f166cfc,
title = "Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins",
abstract = "Fluorescent, DNA-stabilized silver nanoclusters (DNA-AgNCs) are applied in a range of applications within nanoscience and nanotechnology. However, their diverse optical properties, mechanism of formation, and aspects of their composition remain unexplored, making the rational design of nanocluster probes challenging. Here, a synthetic procedure is described for obtaining a high yield of emissive DNA-AgNCs with a C-loop hairpin DNA sequence, with subsequent purification by size-exclusion chromatography (SEC). Through a combination of optical spectroscopy, gel electrophoresis, ICP-MS, and small-angle X-ray scattering (SAXS) in conjunction with the systematic study of various DNA sequences, the low-resolution structure and mechanism of the formation of AgNCs were investigated. Data indicate that fluorescent DNA-AgNCs self-assemble via a head-to-head binding of two DNA hairpins, bridged by a silver nanocluster, resulting in the modelling of a dimeric structure harboring an Ag 12 cluster.",
author = "Reka Geczy and Christensen, {Niels Johan} and Rasmussen, {Kim K} and Ildik{\'o} K{\'a}lomista and Tiwari, {Manish K} and Pratik Shah and Yang, {Seong Wook} and Bjerrum, {Morten J} and Thulstrup, {Peter Waaben}",
note = "{\textcopyright} 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2020",
doi = "10.1002/anie.202005102",
language = "English",
volume = "59",
pages = "16091--16097",
journal = "Angewandte Chemie International Edition",
issn = "1433-7851",
publisher = "Wiley-VCH Verlag GmbH & Co. KGaA",
number = "37",

}

RIS

TY - JOUR

T1 - Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins

AU - Geczy, Reka

AU - Christensen, Niels Johan

AU - Rasmussen, Kim K

AU - Kálomista, Ildikó

AU - Tiwari, Manish K

AU - Shah, Pratik

AU - Yang, Seong Wook

AU - Bjerrum, Morten J

AU - Thulstrup, Peter Waaben

N1 - © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2020

Y1 - 2020

N2 - Fluorescent, DNA-stabilized silver nanoclusters (DNA-AgNCs) are applied in a range of applications within nanoscience and nanotechnology. However, their diverse optical properties, mechanism of formation, and aspects of their composition remain unexplored, making the rational design of nanocluster probes challenging. Here, a synthetic procedure is described for obtaining a high yield of emissive DNA-AgNCs with a C-loop hairpin DNA sequence, with subsequent purification by size-exclusion chromatography (SEC). Through a combination of optical spectroscopy, gel electrophoresis, ICP-MS, and small-angle X-ray scattering (SAXS) in conjunction with the systematic study of various DNA sequences, the low-resolution structure and mechanism of the formation of AgNCs were investigated. Data indicate that fluorescent DNA-AgNCs self-assemble via a head-to-head binding of two DNA hairpins, bridged by a silver nanocluster, resulting in the modelling of a dimeric structure harboring an Ag 12 cluster.

AB - Fluorescent, DNA-stabilized silver nanoclusters (DNA-AgNCs) are applied in a range of applications within nanoscience and nanotechnology. However, their diverse optical properties, mechanism of formation, and aspects of their composition remain unexplored, making the rational design of nanocluster probes challenging. Here, a synthetic procedure is described for obtaining a high yield of emissive DNA-AgNCs with a C-loop hairpin DNA sequence, with subsequent purification by size-exclusion chromatography (SEC). Through a combination of optical spectroscopy, gel electrophoresis, ICP-MS, and small-angle X-ray scattering (SAXS) in conjunction with the systematic study of various DNA sequences, the low-resolution structure and mechanism of the formation of AgNCs were investigated. Data indicate that fluorescent DNA-AgNCs self-assemble via a head-to-head binding of two DNA hairpins, bridged by a silver nanocluster, resulting in the modelling of a dimeric structure harboring an Ag 12 cluster.

U2 - 10.1002/anie.202005102

DO - 10.1002/anie.202005102

M3 - Journal article

C2 - 32516466

VL - 59

SP - 16091

EP - 16097

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

SN - 1433-7851

IS - 37

ER -

ID: 243343590