Fish oil supplementation in pregnancy and neurodevelopment in childhood - A randomized clinical trial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

A double-blind randomized controlled trial of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation or matching placebo during third trimester of pregnancy was conducted within the COPSAC2010 mother-child cohort consisting of 736 women and their children. The objective was to determine if maternal n-3 LCPUFA pregnancy supplementation affects offspring neurodevelopment until 6 years. Neurodevelopment was evaluated in 654 children assessing age of motor milestone achievement, language development, cognitive development, general neurodevelopment, and emotional and behavioral problems. Maternal n-3 LCPUFA supplementation during pregnancy improved early language development and reduced the impact of emotional and behavioral problems. The n-3 LCPUFA supplementation was in boys associated with the earlier achievement of gross motor milestones, improved cognitive development, and a reduced impact of emotional and behavioral problems.

TidsskriftChild Development
Udgave nummer4
Sider (fra-til)1624-1635
Antal sider12
StatusUdgivet - 2021

Bibliografisk note

CURIS 2021 NEXS 040

ID: 255887746