Fighting cancer using an oncofetal glycosaminoglycan-binding protein from malaria parasites

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Agerbæk, Mette Ørskov
Sara Bang-Christensen
Salanti, Ali

Malaria research has led to the discovery of oncofetal chondroitin sulfate, which appears to be shared between placental trophoblasts and cancer cells and can be detected by the evolutionary refined malaria protein VAR2CSA. Interestingly, using recombinant VAR2CSA to target oncofetal chondroitin sulfate shows promise for novel cancer diagnostics and therapeutics.

Originalsprog	Engelsk
Tidsskrift	Trends in Parasitology
Vol/bind	35
Udgave nummer	3
Sider (fra-til)	178-181
ISSN	1471-4922
DOI	https://doi.org/10.1016/j.pt.2018.11.004
Status	Udgivet - 2019

ID: 212857987