Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device: Importance of Myocardial Recovery

Publikation: Bidrag til tidsskriftReviewfagfællebedømt

Standard

Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device : Importance of Myocardial Recovery. / Dridi, Nadia Paarup; Vishram-Nielsen, Julie K.K.; Gustafsson, Finn.

I: Journal of Cardiac Failure, Bind 27, Nr. 4, 2021, s. 486-493.

Publikation: Bidrag til tidsskriftReviewfagfællebedømt

Harvard

Dridi, NP, Vishram-Nielsen, JKK & Gustafsson, F 2021, 'Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device: Importance of Myocardial Recovery', Journal of Cardiac Failure, bind 27, nr. 4, s. 486-493. https://doi.org/10.1016/j.cardfail.2020.12.005

APA

Dridi, N. P., Vishram-Nielsen, J. K. K., & Gustafsson, F. (2021). Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device: Importance of Myocardial Recovery. Journal of Cardiac Failure, 27(4), 486-493. https://doi.org/10.1016/j.cardfail.2020.12.005

Vancouver

Dridi NP, Vishram-Nielsen JKK, Gustafsson F. Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device: Importance of Myocardial Recovery. Journal of Cardiac Failure. 2021;27(4):486-493. https://doi.org/10.1016/j.cardfail.2020.12.005

Author

Dridi, Nadia Paarup ; Vishram-Nielsen, Julie K.K. ; Gustafsson, Finn. / Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device : Importance of Myocardial Recovery. I: Journal of Cardiac Failure. 2021 ; Bind 27, Nr. 4. s. 486-493.

Bibtex

@article{bbd4d0a22c244b529b582364f7a8bbc5,
title = "Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device: Importance of Myocardial Recovery",
abstract = "The number of patients supported with left ventricular assist devices (LVADs) is growing and support times are increasing. This has led to a greater focus on functional capacity of these patients. LVADs greatly improve heart failure symptoms, but surprisingly, improvement in peak oxygen uptake (pVO2) is small and remains decreased at approximately 50% of normal values. Inadequate increase in cardiac output during exercise is the main responsible factor for the low pVO2 in LVAD recipients. Some patients experience LV recovery during mechanical unloading and these patients have a higher pVO2. Here we review the various components determining exercise cardiac output in LVAD recipients and discuss the potential impact of cardiac recovery on these components. LV recovery may affect several components, leading to improved hemodynamics during exercise and, in turn, physical capacity in patients with advanced heart failure undergoing LVAD implantation.",
keywords = "Continuous flow left ventricular assist device, exercise, myocardial recovery, work intolerance",
author = "Dridi, {Nadia Paarup} and Vishram-Nielsen, {Julie K.K.} and Finn Gustafsson",
year = "2021",
doi = "10.1016/j.cardfail.2020.12.005",
language = "English",
volume = "27",
pages = "486--493",
journal = "Journal of Cardiac Failure",
issn = "1071-9164",
publisher = "Churchill Livingstone",
number = "4",

}

RIS

TY - JOUR

T1 - Exercise Tolerance in Patients Treated With a Durable Left Ventricular Assist Device

T2 - Importance of Myocardial Recovery

AU - Dridi, Nadia Paarup

AU - Vishram-Nielsen, Julie K.K.

AU - Gustafsson, Finn

PY - 2021

Y1 - 2021

N2 - The number of patients supported with left ventricular assist devices (LVADs) is growing and support times are increasing. This has led to a greater focus on functional capacity of these patients. LVADs greatly improve heart failure symptoms, but surprisingly, improvement in peak oxygen uptake (pVO2) is small and remains decreased at approximately 50% of normal values. Inadequate increase in cardiac output during exercise is the main responsible factor for the low pVO2 in LVAD recipients. Some patients experience LV recovery during mechanical unloading and these patients have a higher pVO2. Here we review the various components determining exercise cardiac output in LVAD recipients and discuss the potential impact of cardiac recovery on these components. LV recovery may affect several components, leading to improved hemodynamics during exercise and, in turn, physical capacity in patients with advanced heart failure undergoing LVAD implantation.

AB - The number of patients supported with left ventricular assist devices (LVADs) is growing and support times are increasing. This has led to a greater focus on functional capacity of these patients. LVADs greatly improve heart failure symptoms, but surprisingly, improvement in peak oxygen uptake (pVO2) is small and remains decreased at approximately 50% of normal values. Inadequate increase in cardiac output during exercise is the main responsible factor for the low pVO2 in LVAD recipients. Some patients experience LV recovery during mechanical unloading and these patients have a higher pVO2. Here we review the various components determining exercise cardiac output in LVAD recipients and discuss the potential impact of cardiac recovery on these components. LV recovery may affect several components, leading to improved hemodynamics during exercise and, in turn, physical capacity in patients with advanced heart failure undergoing LVAD implantation.

KW - Continuous flow left ventricular assist device

KW - exercise

KW - myocardial recovery

KW - work intolerance

U2 - 10.1016/j.cardfail.2020.12.005

DO - 10.1016/j.cardfail.2020.12.005

M3 - Review

C2 - 33347995

AN - SCOPUS:85099165610

VL - 27

SP - 486

EP - 493

JO - Journal of Cardiac Failure

JF - Journal of Cardiac Failure

SN - 1071-9164

IS - 4

ER -

ID: 255352826