Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients
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Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients. / Hendriksen, K V; Jensen, Tonny Joran; Oturai, P; Feldt-Rasmussen, B.
I: Diabetologia, Bind 55, Nr. 1, 2012, s. 46-50.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients
AU - Hendriksen, K V
AU - Jensen, Tonny Joran
AU - Oturai, P
AU - Feldt-Rasmussen, B
PY - 2012
Y1 - 2012
N2 - In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.
AB - In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.
U2 - 10.1007/s00125-011-2345-8
DO - 10.1007/s00125-011-2345-8
M3 - Journal article
C2 - 22002075
VL - 55
SP - 46
EP - 50
JO - Diabetologia
JF - Diabetologia
SN - 0012-186X
IS - 1
ER -
ID: 48445263