Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure

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Standard

Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure. / Gustafsson, Finn; Torp-Pedersen, Christian; Seibaek, Marie; Burchardt, Hans; Køber, Lars; DIAMOND Study Group.

I: European Heart Journal, Bind 25, Nr. 19, 2004, s. 1711-7.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Gustafsson, F, Torp-Pedersen, C, Seibaek, M, Burchardt, H, Køber, L & DIAMOND Study Group 2004, 'Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure', European Heart Journal, bind 25, nr. 19, s. 1711-7. https://doi.org/10.1016/j.ehj.2004.07.007

APA

Gustafsson, F., Torp-Pedersen, C., Seibaek, M., Burchardt, H., Køber, L., & DIAMOND Study Group (2004). Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure. European Heart Journal, 25(19), 1711-7. https://doi.org/10.1016/j.ehj.2004.07.007

Vancouver

Gustafsson F, Torp-Pedersen C, Seibaek M, Burchardt H, Køber L, DIAMOND Study Group. Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure. European Heart Journal. 2004;25(19):1711-7. https://doi.org/10.1016/j.ehj.2004.07.007

Author

Gustafsson, Finn ; Torp-Pedersen, Christian ; Seibaek, Marie ; Burchardt, Hans ; Køber, Lars ; DIAMOND Study Group. / Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure. I: European Heart Journal. 2004 ; Bind 25, Nr. 19. s. 1711-7.

Bibtex

@article{7f2aa8c0118c11df803f000ea68e967b,
title = "Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure",
abstract = "AIMS: To describe the association between age and risk factors in patients hospitalised with congestive heart failure (CHF) and to determine the effect of age on mortality. METHODS AND RESULTS: Consecutive patients admitted to 34 hospitals with CHF during a period of 2 years were registered. Mean age was 71.7+/-10.2 years, 60% were male and 63% were in NYHA class III-IV. Moderate to severe left ventricular (LV) systolic dysfunction was present in 41%. Short and long-term survival status was obtained after 30 days and 5-8 years, respectively. Older patients less frequently had LV systolic dysfunction, were under treated with ACE-inhibitors and were more often female. The prevalence of hypertension, diabetes and ischaemic heart disease increased with age, until the oldest age group (>80 years). Age was an independent predictor of short-term mortality (risk ratio (RR) per 10-year increase was 1.23 (95% CI 1.04-1.47)). Advancing age significantly increased long-term mortality (RR 1.55 (1.50-1.61)). Age interacted with the LV ejection fraction (P = 0.003). In patients with LV systolic dysfunction, the RR per 10-year increase was 1.29 (1.19-1.39) whereas in patients with preserved systolic function the RR was 1.57 (1.43-1.72, multivariate analyses). CONCLUSION: The clinical characteristics of CHF patients vary considerably with age. Elderly patients hospitalised with CHF face a very grave prognosis, particularly if their heart failure symptoms are caused by LV systolic dysfunction.",
author = "Finn Gustafsson and Christian Torp-Pedersen and Marie Seibaek and Hans Burchardt and Lars K{\o}ber and {DIAMOND Study Group}",
note = "Keywords: Age Factors; Aged; Aged, 80 and over; Female; Follow-Up Studies; Heart Failure; Hospital Mortality; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Ischemia",
year = "2004",
doi = "10.1016/j.ehj.2004.07.007",
language = "English",
volume = "25",
pages = "1711--7",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "19",

}

RIS

TY - JOUR

T1 - Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure

AU - Gustafsson, Finn

AU - Torp-Pedersen, Christian

AU - Seibaek, Marie

AU - Burchardt, Hans

AU - Køber, Lars

AU - DIAMOND Study Group

N1 - Keywords: Age Factors; Aged; Aged, 80 and over; Female; Follow-Up Studies; Heart Failure; Hospital Mortality; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Ischemia

PY - 2004

Y1 - 2004

N2 - AIMS: To describe the association between age and risk factors in patients hospitalised with congestive heart failure (CHF) and to determine the effect of age on mortality. METHODS AND RESULTS: Consecutive patients admitted to 34 hospitals with CHF during a period of 2 years were registered. Mean age was 71.7+/-10.2 years, 60% were male and 63% were in NYHA class III-IV. Moderate to severe left ventricular (LV) systolic dysfunction was present in 41%. Short and long-term survival status was obtained after 30 days and 5-8 years, respectively. Older patients less frequently had LV systolic dysfunction, were under treated with ACE-inhibitors and were more often female. The prevalence of hypertension, diabetes and ischaemic heart disease increased with age, until the oldest age group (>80 years). Age was an independent predictor of short-term mortality (risk ratio (RR) per 10-year increase was 1.23 (95% CI 1.04-1.47)). Advancing age significantly increased long-term mortality (RR 1.55 (1.50-1.61)). Age interacted with the LV ejection fraction (P = 0.003). In patients with LV systolic dysfunction, the RR per 10-year increase was 1.29 (1.19-1.39) whereas in patients with preserved systolic function the RR was 1.57 (1.43-1.72, multivariate analyses). CONCLUSION: The clinical characteristics of CHF patients vary considerably with age. Elderly patients hospitalised with CHF face a very grave prognosis, particularly if their heart failure symptoms are caused by LV systolic dysfunction.

AB - AIMS: To describe the association between age and risk factors in patients hospitalised with congestive heart failure (CHF) and to determine the effect of age on mortality. METHODS AND RESULTS: Consecutive patients admitted to 34 hospitals with CHF during a period of 2 years were registered. Mean age was 71.7+/-10.2 years, 60% were male and 63% were in NYHA class III-IV. Moderate to severe left ventricular (LV) systolic dysfunction was present in 41%. Short and long-term survival status was obtained after 30 days and 5-8 years, respectively. Older patients less frequently had LV systolic dysfunction, were under treated with ACE-inhibitors and were more often female. The prevalence of hypertension, diabetes and ischaemic heart disease increased with age, until the oldest age group (>80 years). Age was an independent predictor of short-term mortality (risk ratio (RR) per 10-year increase was 1.23 (95% CI 1.04-1.47)). Advancing age significantly increased long-term mortality (RR 1.55 (1.50-1.61)). Age interacted with the LV ejection fraction (P = 0.003). In patients with LV systolic dysfunction, the RR per 10-year increase was 1.29 (1.19-1.39) whereas in patients with preserved systolic function the RR was 1.57 (1.43-1.72, multivariate analyses). CONCLUSION: The clinical characteristics of CHF patients vary considerably with age. Elderly patients hospitalised with CHF face a very grave prognosis, particularly if their heart failure symptoms are caused by LV systolic dysfunction.

U2 - 10.1016/j.ehj.2004.07.007

DO - 10.1016/j.ehj.2004.07.007

M3 - Journal article

C2 - 15451149

VL - 25

SP - 1711

EP - 1717

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 19

ER -

ID: 17397041