TY - JOUR

T1 - Effect of aerobic exercise training on asthma in adults: A systematic review and meta-analysis

AU - Hansen, Erik Søren Halvard

AU - Pitzner-Fabricius, Anders

AU - Tønnesen, Louise Lindhardt

AU - Rasmusen, Hanne Kruuse

AU - Hostrup, Morten

AU - Hellsten, Ylva

AU - Backer, Vibeke

AU - Henriksen, Marius

N1 - Copyright ©ERS 2020.

PY - 2020

Y1 - 2020

N2 - Objective: To evaluate the effect of aerobic exercise training on asthma control, lung function and airway inflammation in adults with asthma.Design: Systematic review and meta-analysis.Methods: Randomised controlled trials investigating the effect of ⩾ 8 weeks of aerobic exercise training on outcomes for asthma control, lung function and airway inflammation in adults with asthma were eligible for study. MEDLINE, Embase, CINAHL, PEDro and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to April 3, 2019. Risk of bias was assessed using the Cochrane Risk of Bias Tool.Results: We included 11 studies with a total of 543 adults with asthma. Participants' mean (range) age was 36.5 (22-54) years; 74.8% of participants were women and the mean (range) body mass index was 27.6 (23.2-38.1) kg·m-2. Interventions had a median (range) duration of 12 (8-12) weeks and included walking, jogging, spinning, treadmill running and other unspecified exercise training programmes. Exercise training improved asthma control with a standard mean difference (SMD) of -0.48 (-0.81 - -0.16). Lung function slightly increased with an SMD of -0.36 (-0.72-0.00) in favour of exercise training. Exercise training had no apparent effect on markers of airway inflammation SMD: -0.03 (-0.41-0.36).Conclusions: In adults with asthma, aerobic exercise training has potential to improve asthma control and lung function, but not airway inflammation.

AB - Objective: To evaluate the effect of aerobic exercise training on asthma control, lung function and airway inflammation in adults with asthma.Design: Systematic review and meta-analysis.Methods: Randomised controlled trials investigating the effect of ⩾ 8 weeks of aerobic exercise training on outcomes for asthma control, lung function and airway inflammation in adults with asthma were eligible for study. MEDLINE, Embase, CINAHL, PEDro and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to April 3, 2019. Risk of bias was assessed using the Cochrane Risk of Bias Tool.Results: We included 11 studies with a total of 543 adults with asthma. Participants' mean (range) age was 36.5 (22-54) years; 74.8% of participants were women and the mean (range) body mass index was 27.6 (23.2-38.1) kg·m-2. Interventions had a median (range) duration of 12 (8-12) weeks and included walking, jogging, spinning, treadmill running and other unspecified exercise training programmes. Exercise training improved asthma control with a standard mean difference (SMD) of -0.48 (-0.81 - -0.16). Lung function slightly increased with an SMD of -0.36 (-0.72-0.00) in favour of exercise training. Exercise training had no apparent effect on markers of airway inflammation SMD: -0.03 (-0.41-0.36).Conclusions: In adults with asthma, aerobic exercise training has potential to improve asthma control and lung function, but not airway inflammation.

U2 - 10.1183/13993003.00146-2020

DO - 10.1183/13993003.00146-2020

M3 - Review

C2 - 32350100

VL - 56

JO - The European Respiratory Journal

JF - The European Respiratory Journal

SN - 0903-1936

IS - 1

M1 - 2000146

ER -