Drug Target Commons 2.0: a community platform for systematic analysis of drug-target interaction profiles

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

  • Ziaur Rehman Tanoli
  • Zaid Alam
  • Markus Vähä-Koskela
  • Balaguru Ravikumar
  • Alina Malyutina
  • Alok Jaiswal
  • Jing Tang
  • Wennerberg, Krister
  • Tero Aittokallio

Drug Target Commons (DTC) is a web platform (database with user interface) for community-driven bioactivity data integration and standardization for comprehensive mapping, reuse and analysis of compound-target interaction profiles. End users can search, upload, edit, annotate and export expert-curated bioactivity data for further analysis, using an application programmable interface, database dump or tab-delimited text download options. To guide chemical biology and drug-repurposing applications, DTC version 2.0 includes updated clinical development information for the compounds and target gene-disease associations, as well as cancer-type indications for mutant protein targets, which are critical for precision oncology developments.

OriginalsprogEngelsk
Artikelnummerbay083
TidsskriftDatabase: The Journal of Biological Databases and Curation
Vol/bind2018
Udgave nummer2018
Sider (fra-til)1-13
Antal sider13
ISSN1758-0463
DOI
StatusUdgivet - 2018

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