Drosophila as a Model to Study the Link between Metabolism and Cancer

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Drosophila as a Model to Study the Link between Metabolism and Cancer. / Herranz, Hector; Cohen, Stephen M.

I: Journal of Developmental Biology, Bind 5, Nr. 4, 15, 12.2017.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Herranz, H & Cohen, SM 2017, 'Drosophila as a Model to Study the Link between Metabolism and Cancer', Journal of Developmental Biology, bind 5, nr. 4, 15. https://doi.org/10.3390/jdb5040015

APA

Herranz, H., & Cohen, S. M. (2017). Drosophila as a Model to Study the Link between Metabolism and Cancer. Journal of Developmental Biology, 5(4), [15]. https://doi.org/10.3390/jdb5040015

Vancouver

Herranz H, Cohen SM. Drosophila as a Model to Study the Link between Metabolism and Cancer. Journal of Developmental Biology. 2017 dec.;5(4). 15. https://doi.org/10.3390/jdb5040015

Author

Herranz, Hector ; Cohen, Stephen M. / Drosophila as a Model to Study the Link between Metabolism and Cancer. I: Journal of Developmental Biology. 2017 ; Bind 5, Nr. 4.

Bibtex

@article{fd285bc47fa3443bb23434e90016c338,
title = "Drosophila as a Model to Study the Link between Metabolism and Cancer",
abstract = "Cellular metabolism has recently been recognized as a hallmark of cancer. Investigating the origin and effects of the reprogrammed metabolism of tumor cells, and identifying its genetic mediators, will improve our understanding of how these changes contribute to disease progression and may suggest new approaches to therapy. Drosophila melanogaster is emerging as a valuable model to study multiple aspects of tumor formation and malignant transformation. In this review, we discuss the use of Drosophila as model to study how changes in cellular metabolism, as well as metabolic disease, contribute to cancer.",
keywords = "Drosophila, animal model, metabolism, cancer, Warburg effect, obesity, type 2 diabetes",
author = "Hector Herranz and Cohen, {Stephen M.}",
year = "2017",
month = dec,
doi = "10.3390/jdb5040015",
language = "English",
volume = "5",
journal = "Journal of Developmental Biology",
publisher = "Trade Science, Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Drosophila as a Model to Study the Link between Metabolism and Cancer

AU - Herranz, Hector

AU - Cohen, Stephen M.

PY - 2017/12

Y1 - 2017/12

N2 - Cellular metabolism has recently been recognized as a hallmark of cancer. Investigating the origin and effects of the reprogrammed metabolism of tumor cells, and identifying its genetic mediators, will improve our understanding of how these changes contribute to disease progression and may suggest new approaches to therapy. Drosophila melanogaster is emerging as a valuable model to study multiple aspects of tumor formation and malignant transformation. In this review, we discuss the use of Drosophila as model to study how changes in cellular metabolism, as well as metabolic disease, contribute to cancer.

AB - Cellular metabolism has recently been recognized as a hallmark of cancer. Investigating the origin and effects of the reprogrammed metabolism of tumor cells, and identifying its genetic mediators, will improve our understanding of how these changes contribute to disease progression and may suggest new approaches to therapy. Drosophila melanogaster is emerging as a valuable model to study multiple aspects of tumor formation and malignant transformation. In this review, we discuss the use of Drosophila as model to study how changes in cellular metabolism, as well as metabolic disease, contribute to cancer.

KW - Drosophila

KW - animal model

KW - metabolism

KW - cancer

KW - Warburg effect

KW - obesity

KW - type 2 diabetes

U2 - 10.3390/jdb5040015

DO - 10.3390/jdb5040015

M3 - Journal article

C2 - 29615570

VL - 5

JO - Journal of Developmental Biology

JF - Journal of Developmental Biology

IS - 4

M1 - 15

ER -

ID: 188481760