The title compound, C₁₇H₂₁BrO₆, was prepared by nucleophilic alkylation of 1-bromo-3,4-bis(bromomethyl)-2,5- dimethoxybenzene. It crystallizes with two independent molecules in the asymmetric unit. The bond lengths and angles are generally within the normal ranges. The crystal packing is stabilized by weak intermolecular C-H⋯O hydrogen bonds and weak C-H⋯π (arene) interactions.