Depression After First Hospital Admission for Acute Coronary Syndrome: A Study of Time of Onset and Impact on Survival

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Depression After First Hospital Admission for Acute Coronary Syndrome : A Study of Time of Onset and Impact on Survival. / Osler, Merete; Mårtensson, Solvej; Wium-Andersen, Ida Kim; Prescott, Eva; Andersen, Per Kragh; Jørgensen, Terese Sara Høj; Carlsen, Kathrine; Wium-Andersen, Marie Kim; Jørgensen, Martin Balslev.

I: American Journal of Epidemiology, Bind 183, Nr. 3, 01.02.2016, s. 218-226.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Osler, M, Mårtensson, S, Wium-Andersen, IK, Prescott, E, Andersen, PK, Jørgensen, TSH, Carlsen, K, Wium-Andersen, MK & Jørgensen, MB 2016, 'Depression After First Hospital Admission for Acute Coronary Syndrome: A Study of Time of Onset and Impact on Survival', American Journal of Epidemiology, bind 183, nr. 3, s. 218-226. https://doi.org/10.1093/aje/kwv227

APA

Osler, M., Mårtensson, S., Wium-Andersen, I. K., Prescott, E., Andersen, P. K., Jørgensen, T. S. H., ... Jørgensen, M. B. (2016). Depression After First Hospital Admission for Acute Coronary Syndrome: A Study of Time of Onset and Impact on Survival. American Journal of Epidemiology, 183(3), 218-226. https://doi.org/10.1093/aje/kwv227

Vancouver

Osler M, Mårtensson S, Wium-Andersen IK, Prescott E, Andersen PK, Jørgensen TSH o.a. Depression After First Hospital Admission for Acute Coronary Syndrome: A Study of Time of Onset and Impact on Survival. American Journal of Epidemiology. 2016 feb 1;183(3):218-226. https://doi.org/10.1093/aje/kwv227

Author

Osler, Merete ; Mårtensson, Solvej ; Wium-Andersen, Ida Kim ; Prescott, Eva ; Andersen, Per Kragh ; Jørgensen, Terese Sara Høj ; Carlsen, Kathrine ; Wium-Andersen, Marie Kim ; Jørgensen, Martin Balslev. / Depression After First Hospital Admission for Acute Coronary Syndrome : A Study of Time of Onset and Impact on Survival. I: American Journal of Epidemiology. 2016 ; Bind 183, Nr. 3. s. 218-226.

Bibtex

@article{34c314a5ff9e4420a7f1243e01069fb1,
title = "Depression After First Hospital Admission for Acute Coronary Syndrome: A Study of Time of Onset and Impact on Survival",
abstract = "We examined incidence of depression after acute coronary syndrome (ACS) and whether the timing of depression onset influenced survival. All first-time hospitalizations for ACS (n = 97,793) identified in the Danish Patient Registry during 2001-2009 and a reference population were followed for depression and mortality via linkage to patient, prescription, and cause-of-death registries until the end of 2012. Incidence of depression (as defined by hospital discharge or antidepressant medication use) and the relationship between depression and mortality were examined using time-to-event models. In total, 19,520 (20.0{\%}) ACS patients experienced depression within 2 years after the event. The adjusted rate ratio for depression in ACS patients compared with the reference population was 1.28 (95{\%} confidence interval (CI): 1.25, 1.30). During 12 years of follow-up, 39,523 (40.4{\%}) ACS patients and 27,931 (28.6{\%}) of the reference population died. ACS patients with recurrent (hazard ratio (HR) = 1.62, 95{\%} CI: 1.57, 1.67) or new-onset (HR = 1.66, 95{\%} CI: 1.60, 1.72) depression had higher mortality rates than patients with no depression. In the reference population, the corresponding relative estimates for recurrent (HR =1.98, 95{\%} CI: 1.92, 2.05) and new-onset (HR = 2.42, 95{\%} CI: 2.31, 2.54) depression were stronger. Depression is common in ACS patients and is associated with increased mortality independently of time of onset, but here the excess mortality associated with depression seemed to be lower in ACS patients than in the reference population.",
author = "Merete Osler and Solvej M{\aa}rtensson and Wium-Andersen, {Ida Kim} and Eva Prescott and Andersen, {Per Kragh} and J{\o}rgensen, {Terese Sara H{\o}j} and Kathrine Carlsen and Wium-Andersen, {Marie Kim} and J{\o}rgensen, {Martin Balslev}",
note = "{\circledC} The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",
year = "2016",
month = "2",
day = "1",
doi = "10.1093/aje/kwv227",
language = "English",
volume = "183",
pages = "218--226",
journal = "American Journal of Epidemiology",
issn = "0002-9262",
publisher = "Oxford University Press",
number = "3",

}

RIS

TY - JOUR

T1 - Depression After First Hospital Admission for Acute Coronary Syndrome

T2 - A Study of Time of Onset and Impact on Survival

AU - Osler, Merete

AU - Mårtensson, Solvej

AU - Wium-Andersen, Ida Kim

AU - Prescott, Eva

AU - Andersen, Per Kragh

AU - Jørgensen, Terese Sara Høj

AU - Carlsen, Kathrine

AU - Wium-Andersen, Marie Kim

AU - Jørgensen, Martin Balslev

N1 - © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - We examined incidence of depression after acute coronary syndrome (ACS) and whether the timing of depression onset influenced survival. All first-time hospitalizations for ACS (n = 97,793) identified in the Danish Patient Registry during 2001-2009 and a reference population were followed for depression and mortality via linkage to patient, prescription, and cause-of-death registries until the end of 2012. Incidence of depression (as defined by hospital discharge or antidepressant medication use) and the relationship between depression and mortality were examined using time-to-event models. In total, 19,520 (20.0%) ACS patients experienced depression within 2 years after the event. The adjusted rate ratio for depression in ACS patients compared with the reference population was 1.28 (95% confidence interval (CI): 1.25, 1.30). During 12 years of follow-up, 39,523 (40.4%) ACS patients and 27,931 (28.6%) of the reference population died. ACS patients with recurrent (hazard ratio (HR) = 1.62, 95% CI: 1.57, 1.67) or new-onset (HR = 1.66, 95% CI: 1.60, 1.72) depression had higher mortality rates than patients with no depression. In the reference population, the corresponding relative estimates for recurrent (HR =1.98, 95% CI: 1.92, 2.05) and new-onset (HR = 2.42, 95% CI: 2.31, 2.54) depression were stronger. Depression is common in ACS patients and is associated with increased mortality independently of time of onset, but here the excess mortality associated with depression seemed to be lower in ACS patients than in the reference population.

AB - We examined incidence of depression after acute coronary syndrome (ACS) and whether the timing of depression onset influenced survival. All first-time hospitalizations for ACS (n = 97,793) identified in the Danish Patient Registry during 2001-2009 and a reference population were followed for depression and mortality via linkage to patient, prescription, and cause-of-death registries until the end of 2012. Incidence of depression (as defined by hospital discharge or antidepressant medication use) and the relationship between depression and mortality were examined using time-to-event models. In total, 19,520 (20.0%) ACS patients experienced depression within 2 years after the event. The adjusted rate ratio for depression in ACS patients compared with the reference population was 1.28 (95% confidence interval (CI): 1.25, 1.30). During 12 years of follow-up, 39,523 (40.4%) ACS patients and 27,931 (28.6%) of the reference population died. ACS patients with recurrent (hazard ratio (HR) = 1.62, 95% CI: 1.57, 1.67) or new-onset (HR = 1.66, 95% CI: 1.60, 1.72) depression had higher mortality rates than patients with no depression. In the reference population, the corresponding relative estimates for recurrent (HR =1.98, 95% CI: 1.92, 2.05) and new-onset (HR = 2.42, 95% CI: 2.31, 2.54) depression were stronger. Depression is common in ACS patients and is associated with increased mortality independently of time of onset, but here the excess mortality associated with depression seemed to be lower in ACS patients than in the reference population.

U2 - 10.1093/aje/kwv227

DO - 10.1093/aje/kwv227

M3 - Journal article

C2 - 26740025

VL - 183

SP - 218

EP - 226

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

SN - 0002-9262

IS - 3

ER -

ID: 154183570