Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study

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Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study. / Gudbergsen, H; Lohmander, L S; Jones, G; Christensen, R; Bartels, E M; Danneskiold-Samsøe, B; Bliddal, H; Boesen, M.

I: Osteoarthritis and Cartilage, Bind 21, Nr. 4, 2013, s. 535-543.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Gudbergsen, H, Lohmander, LS, Jones, G, Christensen, R, Bartels, EM, Danneskiold-Samsøe, B, Bliddal, H & Boesen, M 2013, 'Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study', Osteoarthritis and Cartilage, bind 21, nr. 4, s. 535-543. https://doi.org/10.1016/j.joca.2012.12.010

APA

Gudbergsen, H., Lohmander, L. S., Jones, G., Christensen, R., Bartels, E. M., Danneskiold-Samsøe, B., Bliddal, H., & Boesen, M. (2013). Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study. Osteoarthritis and Cartilage, 21(4), 535-543. https://doi.org/10.1016/j.joca.2012.12.010

Vancouver

Gudbergsen H, Lohmander LS, Jones G, Christensen R, Bartels EM, Danneskiold-Samsøe B o.a. Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study. Osteoarthritis and Cartilage. 2013;21(4):535-543. https://doi.org/10.1016/j.joca.2012.12.010

Author

Gudbergsen, H ; Lohmander, L S ; Jones, G ; Christensen, R ; Bartels, E M ; Danneskiold-Samsøe, B ; Bliddal, H ; Boesen, M. / Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study. I: Osteoarthritis and Cartilage. 2013 ; Bind 21, Nr. 4. s. 535-543.

Bibtex

@article{6f4652e6bace4609b5b88505c1b8dd8d,
title = "Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study",
abstract = "ObjectivesTo assess correlations between Kellgren & Lawrence (KL) gradings, minimum joint space width (mJSW) measurements and the Boston Leeds Osteoarthritis Knee Score (BLOKS) within a cohort of obese patients with knee osteoarthritis (KOA).Methods192 Participants were recruited from an outpatient clinic (ClinicalTrials.gov: NCT00655941). Inclusion criteria were age ≥50 years, body mass index (BMI) ≥30 kg/m2 plus symptomatic and verified KOA. 1.5 T magnetic resonance imaging (MRI) scans were assessed using BLOKS and bi-plane radiography by mJSW and KL. Statistics used were Spearman rank correlation coefficients.ResultsThe average patient was 63 years of age, female and had a BMI of 37. KL gradings correlated to cartilage damage, bone marrow lesions and meniscus pathology (r = 0.15–0.76) and similar results were found for the relationship between BLOKS and mJSW. BLOKS assessed knee joint pathology co-segregated with compartment and grade specific KL (P < 0.0001). BLOKS variables were statistically significant correlated, particularly in the medial tibiofemoral compartment (r = 0.42–0.80). Adjusting for age, gender and BMI did not alter these associations.ConclusionExtensive pathological damage is present even in mild radiographic KOA and BLOKS gradings and KL scores increase together. Analyses of compartment specific KL scores revealed differences in their relationship to the assessed MRI variables. Our study displays the segregation of MRI gradings with respect to location and level of radiographic scores, reveals a high inter-dependency of MRI-assessed structures, and describes some redundancy of specific BLOKS variables.",
author = "H Gudbergsen and Lohmander, {L S} and G Jones and R Christensen and Bartels, {E M} and B Danneskiold-Sams{\o}e and H Bliddal and M Boesen",
year = "2013",
doi = "10.1016/j.joca.2012.12.010",
language = "English",
volume = "21",
pages = "535--543",
journal = "Osteoarthritis and Cartilage",
issn = "1063-4584",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Correlations between radiographic assessments and MRI features of knee osteoarthritis--a cross-sectional study

AU - Gudbergsen, H

AU - Lohmander, L S

AU - Jones, G

AU - Christensen, R

AU - Bartels, E M

AU - Danneskiold-Samsøe, B

AU - Bliddal, H

AU - Boesen, M

PY - 2013

Y1 - 2013

N2 - ObjectivesTo assess correlations between Kellgren & Lawrence (KL) gradings, minimum joint space width (mJSW) measurements and the Boston Leeds Osteoarthritis Knee Score (BLOKS) within a cohort of obese patients with knee osteoarthritis (KOA).Methods192 Participants were recruited from an outpatient clinic (ClinicalTrials.gov: NCT00655941). Inclusion criteria were age ≥50 years, body mass index (BMI) ≥30 kg/m2 plus symptomatic and verified KOA. 1.5 T magnetic resonance imaging (MRI) scans were assessed using BLOKS and bi-plane radiography by mJSW and KL. Statistics used were Spearman rank correlation coefficients.ResultsThe average patient was 63 years of age, female and had a BMI of 37. KL gradings correlated to cartilage damage, bone marrow lesions and meniscus pathology (r = 0.15–0.76) and similar results were found for the relationship between BLOKS and mJSW. BLOKS assessed knee joint pathology co-segregated with compartment and grade specific KL (P < 0.0001). BLOKS variables were statistically significant correlated, particularly in the medial tibiofemoral compartment (r = 0.42–0.80). Adjusting for age, gender and BMI did not alter these associations.ConclusionExtensive pathological damage is present even in mild radiographic KOA and BLOKS gradings and KL scores increase together. Analyses of compartment specific KL scores revealed differences in their relationship to the assessed MRI variables. Our study displays the segregation of MRI gradings with respect to location and level of radiographic scores, reveals a high inter-dependency of MRI-assessed structures, and describes some redundancy of specific BLOKS variables.

AB - ObjectivesTo assess correlations between Kellgren & Lawrence (KL) gradings, minimum joint space width (mJSW) measurements and the Boston Leeds Osteoarthritis Knee Score (BLOKS) within a cohort of obese patients with knee osteoarthritis (KOA).Methods192 Participants were recruited from an outpatient clinic (ClinicalTrials.gov: NCT00655941). Inclusion criteria were age ≥50 years, body mass index (BMI) ≥30 kg/m2 plus symptomatic and verified KOA. 1.5 T magnetic resonance imaging (MRI) scans were assessed using BLOKS and bi-plane radiography by mJSW and KL. Statistics used were Spearman rank correlation coefficients.ResultsThe average patient was 63 years of age, female and had a BMI of 37. KL gradings correlated to cartilage damage, bone marrow lesions and meniscus pathology (r = 0.15–0.76) and similar results were found for the relationship between BLOKS and mJSW. BLOKS assessed knee joint pathology co-segregated with compartment and grade specific KL (P < 0.0001). BLOKS variables were statistically significant correlated, particularly in the medial tibiofemoral compartment (r = 0.42–0.80). Adjusting for age, gender and BMI did not alter these associations.ConclusionExtensive pathological damage is present even in mild radiographic KOA and BLOKS gradings and KL scores increase together. Analyses of compartment specific KL scores revealed differences in their relationship to the assessed MRI variables. Our study displays the segregation of MRI gradings with respect to location and level of radiographic scores, reveals a high inter-dependency of MRI-assessed structures, and describes some redundancy of specific BLOKS variables.

U2 - 10.1016/j.joca.2012.12.010

DO - 10.1016/j.joca.2012.12.010

M3 - Journal article

C2 - 23274104

VL - 21

SP - 535

EP - 543

JO - Osteoarthritis and Cartilage

JF - Osteoarthritis and Cartilage

SN - 1063-4584

IS - 4

ER -

ID: 120458891