TY - JOUR

T1 - Copenhagen pancreatitis study

T2 - An interim report from a prospective epidemiological multicentre study

AU - Andersen, Jens Rikardt

AU - Backer, O

AU - Balsløv, J T

AU - Bonnevie, O.

AU - Burcharth, F

AU - Christoffersen, I

AU - Christoffersen, P

AU - Clausen, B

AU - Ehlers, D

AU - Fischermann, K

AU - Frederiksen, H J

AU - Friedberg, R

AU - Hamilton, B

AU - Hardt, F

AU - Hegnhøj, J

AU - Jarnum, S

AU - Jensen, H E

AU - Jess, P

AU - Justesen, T

AU - Kjærgaard, J

AU - Klarskov, P

AU - Krag, E

AU - Madsen, P

AU - Magid, E

AU - Malchow-Møller, A

AU - Marcussen, H

AU - Matzen, P

AU - Nørgaard, B.

AU - Pedersen-Bjergaard, O

AU - Raahave, D

AU - Schmidt, A

AU - Stigsby, B

AU - Teilum, D

AU - Uhrenholdt, A

AU - Villumsen, B

AU - Winkler, K

AU - The Copenhagen Pancreatitis Study Group

N1 - (Ekstern)

PY - 1981

Y1 - 1981

N2 - During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.

AB - During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.

KW - Abdomen, acute condition

KW - Alcohol drinking

KW - Amylase

KW - Blood sugar

KW - Calcium

KW - Cholelithiasis

KW - Epidemiology

KW - Liver disease

KW - Morphine

KW - Pancreatic disease

KW - Pancreatitis

KW - Prospective studies

U2 - 10.3109/00365528109181973

DO - 10.3109/00365528109181973

M3 - Journal article

C2 - 7313541

AN - SCOPUS:0019524138

VL - 16

SP - 305

EP - 312

JO - Scandinavian Journal of Gastroenterology. Supplement

JF - Scandinavian Journal of Gastroenterology. Supplement

SN - 0085-5928

IS - 2

ER -