Cirrhosis patients have increased risk of complications after hip or knee arthroplasty: A Danish population-based cohort study

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Standard

Cirrhosis patients have increased risk of complications after hip or knee arthroplasty : A Danish population-based cohort study. / Deleuran, T.; Vilstrup, H.; Overgaard, Søren; Jepsen, P.

I: Acta Orthopaedica (Print Edition), Bind 86, Nr. 1, 2015, s. 108-113.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Deleuran, T, Vilstrup, H, Overgaard, S & Jepsen, P 2015, 'Cirrhosis patients have increased risk of complications after hip or knee arthroplasty: A Danish population-based cohort study', Acta Orthopaedica (Print Edition), bind 86, nr. 1, s. 108-113. https://doi.org/10.3109/17453674.2014.961397

APA

Deleuran, T., Vilstrup, H., Overgaard, S., & Jepsen, P. (2015). Cirrhosis patients have increased risk of complications after hip or knee arthroplasty: A Danish population-based cohort study. Acta Orthopaedica (Print Edition), 86(1), 108-113. https://doi.org/10.3109/17453674.2014.961397

Vancouver

Deleuran T, Vilstrup H, Overgaard S, Jepsen P. Cirrhosis patients have increased risk of complications after hip or knee arthroplasty: A Danish population-based cohort study. Acta Orthopaedica (Print Edition). 2015;86(1):108-113. https://doi.org/10.3109/17453674.2014.961397

Author

Deleuran, T. ; Vilstrup, H. ; Overgaard, Søren ; Jepsen, P. / Cirrhosis patients have increased risk of complications after hip or knee arthroplasty : A Danish population-based cohort study. I: Acta Orthopaedica (Print Edition). 2015 ; Bind 86, Nr. 1. s. 108-113.

Bibtex

@article{af5bc65d31714f21863cc166b84b980b,
title = "Cirrhosis patients have increased risk of complications after hip or knee arthroplasty: A Danish population-based cohort study",
abstract = "Background and purpose: The risk of complications in cirrhosis patients after orthopedic surgery is unclear. We examined this risk after total hip arthroplasty (THA) or total knee arthroplasty (TKA). Patients and methods: Using Danish healthcare registries, we identified all Danish residents who underwent a THA or TKA for primary osteoarthritis in the period 1995-2011. We compared the risk of complications in patients with or without cirrhosis. Results: The surgical technique was similar in the 363 cirrhosis patients and in 109,159 reference patients, but cirrhosis patients were more likely to have been under general anesthesia (34% vs. 23%), were younger (median age 66 vs. 69 years), had a predominance of males (54% vs. 41%), had more comorbidity, and had had more hospitalizations preoperatively. Their risk of intraoperative complications was similar to that for reference patients (2.5% vs. 2.0%), but they had greater risk of dying during hospitalization or within 30 days of discharge (1.4% vs. 0.4%; aOR = 3.9, 95% CI: 1.5-10); greater risk of postoperative transfer to an intensive care unit (0.6% vs. 0.06%; aOR = 5.8, CI: 1.3-25) or a medical department (4.4% vs. 2.5%; aOR = 1.7, CI: 0.99-2.9); greater risk of readmission within 30 days of discharge (15% vs. 8%; aOR = 1.8, CI: 1.3-2.4); and greater risk of deep prosthetic infection (3.1% vs. 1.4%) or revision (3.7% vs. 1.7%) within 1 year. The chance of having an uncomplicated procedure was 81.0% (CI: 76.6-85.0) for cirrhosis patients and 90.0% (CI: 89.6-90.0) for reference patients. Interpretation: Cirrhosis patients had a higher risk of postoperative complications after THA or TKA for primary osteoarthritis than patients without cirrhosis. This may have implications for orthopedic surgeons' postoperative management of cirrhosis patients, and preoperative assessment by a hepatologist may be indicated.",
author = "T. Deleuran and H. Vilstrup and S{\o}ren Overgaard and P. Jepsen",
year = "2015",
doi = "10.3109/17453674.2014.961397",
language = "English",
volume = "86",
pages = "108--113",
journal = "Acta Orthopaedica",
issn = "1745-3674",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - Cirrhosis patients have increased risk of complications after hip or knee arthroplasty

T2 - A Danish population-based cohort study

AU - Deleuran, T.

AU - Vilstrup, H.

AU - Overgaard, Søren

AU - Jepsen, P.

PY - 2015

Y1 - 2015

N2 - Background and purpose: The risk of complications in cirrhosis patients after orthopedic surgery is unclear. We examined this risk after total hip arthroplasty (THA) or total knee arthroplasty (TKA). Patients and methods: Using Danish healthcare registries, we identified all Danish residents who underwent a THA or TKA for primary osteoarthritis in the period 1995-2011. We compared the risk of complications in patients with or without cirrhosis. Results: The surgical technique was similar in the 363 cirrhosis patients and in 109,159 reference patients, but cirrhosis patients were more likely to have been under general anesthesia (34% vs. 23%), were younger (median age 66 vs. 69 years), had a predominance of males (54% vs. 41%), had more comorbidity, and had had more hospitalizations preoperatively. Their risk of intraoperative complications was similar to that for reference patients (2.5% vs. 2.0%), but they had greater risk of dying during hospitalization or within 30 days of discharge (1.4% vs. 0.4%; aOR = 3.9, 95% CI: 1.5-10); greater risk of postoperative transfer to an intensive care unit (0.6% vs. 0.06%; aOR = 5.8, CI: 1.3-25) or a medical department (4.4% vs. 2.5%; aOR = 1.7, CI: 0.99-2.9); greater risk of readmission within 30 days of discharge (15% vs. 8%; aOR = 1.8, CI: 1.3-2.4); and greater risk of deep prosthetic infection (3.1% vs. 1.4%) or revision (3.7% vs. 1.7%) within 1 year. The chance of having an uncomplicated procedure was 81.0% (CI: 76.6-85.0) for cirrhosis patients and 90.0% (CI: 89.6-90.0) for reference patients. Interpretation: Cirrhosis patients had a higher risk of postoperative complications after THA or TKA for primary osteoarthritis than patients without cirrhosis. This may have implications for orthopedic surgeons' postoperative management of cirrhosis patients, and preoperative assessment by a hepatologist may be indicated.

AB - Background and purpose: The risk of complications in cirrhosis patients after orthopedic surgery is unclear. We examined this risk after total hip arthroplasty (THA) or total knee arthroplasty (TKA). Patients and methods: Using Danish healthcare registries, we identified all Danish residents who underwent a THA or TKA for primary osteoarthritis in the period 1995-2011. We compared the risk of complications in patients with or without cirrhosis. Results: The surgical technique was similar in the 363 cirrhosis patients and in 109,159 reference patients, but cirrhosis patients were more likely to have been under general anesthesia (34% vs. 23%), were younger (median age 66 vs. 69 years), had a predominance of males (54% vs. 41%), had more comorbidity, and had had more hospitalizations preoperatively. Their risk of intraoperative complications was similar to that for reference patients (2.5% vs. 2.0%), but they had greater risk of dying during hospitalization or within 30 days of discharge (1.4% vs. 0.4%; aOR = 3.9, 95% CI: 1.5-10); greater risk of postoperative transfer to an intensive care unit (0.6% vs. 0.06%; aOR = 5.8, CI: 1.3-25) or a medical department (4.4% vs. 2.5%; aOR = 1.7, CI: 0.99-2.9); greater risk of readmission within 30 days of discharge (15% vs. 8%; aOR = 1.8, CI: 1.3-2.4); and greater risk of deep prosthetic infection (3.1% vs. 1.4%) or revision (3.7% vs. 1.7%) within 1 year. The chance of having an uncomplicated procedure was 81.0% (CI: 76.6-85.0) for cirrhosis patients and 90.0% (CI: 89.6-90.0) for reference patients. Interpretation: Cirrhosis patients had a higher risk of postoperative complications after THA or TKA for primary osteoarthritis than patients without cirrhosis. This may have implications for orthopedic surgeons' postoperative management of cirrhosis patients, and preoperative assessment by a hepatologist may be indicated.

U2 - 10.3109/17453674.2014.961397

DO - 10.3109/17453674.2014.961397

M3 - Journal article

C2 - 25238440

VL - 86

SP - 108

EP - 113

JO - Acta Orthopaedica

JF - Acta Orthopaedica

SN - 1745-3674

IS - 1

ER -

ID: 252060449