TY - JOUR

T1 - Children and young people with perinatal HIV in Europe

T2 - epidemiological situation in 2014 and implications for the future

AU - Grarup, Jesper

AU - Kirk, Ole

AU - Lundgren, Jens

AU - Raben, Dorthe

AU - Writing group for the Kids to Adults Working Group and Data Management and Harmonisation Group in EuroCoord

PY - 2016

Y1 - 2016

N2 - Accurate ascertainment of the number of children living with human immunodeficiency virus (HIV) is important to plan paediatric and adolescent health services. In Europe, the first generation of perinatally HIV-infected survivors are transferring to adult care and their health needs are unknown. We undertook an online survey of HIV cohort studies participating in the EuroCoord Network of Excellence to ascertain the number of perinatally HIV-infected (pHIV) patients included, to compare it with those published by the European Centre for Disease Prevention and Control (ECDC) and the World Health Organization (WHO) and to assess the ability of countries to follow up pHIV patients after transfer to adult care. At the end of 2013, 16 countries in EuroCoord reported 8,229 pHIV patients in follow-up in cohorts, compared with 5,160 cumulative diagnoses reported by the ECDC in the same area. Follow-up of pHIV patients after transfer to adult care varied. It is likely that the number of diagnoses of perinatal HIV reported to ECDC is an underestimate, although this varies by country. Further work is needed to refine estimates and encourage follow-up in adult HIV cohorts to investigate long-term outcomes and improve the care of the next generation of children with HIV.

AB - Accurate ascertainment of the number of children living with human immunodeficiency virus (HIV) is important to plan paediatric and adolescent health services. In Europe, the first generation of perinatally HIV-infected survivors are transferring to adult care and their health needs are unknown. We undertook an online survey of HIV cohort studies participating in the EuroCoord Network of Excellence to ascertain the number of perinatally HIV-infected (pHIV) patients included, to compare it with those published by the European Centre for Disease Prevention and Control (ECDC) and the World Health Organization (WHO) and to assess the ability of countries to follow up pHIV patients after transfer to adult care. At the end of 2013, 16 countries in EuroCoord reported 8,229 pHIV patients in follow-up in cohorts, compared with 5,160 cumulative diagnoses reported by the ECDC in the same area. Follow-up of pHIV patients after transfer to adult care varied. It is likely that the number of diagnoses of perinatal HIV reported to ECDC is an underestimate, although this varies by country. Further work is needed to refine estimates and encourage follow-up in adult HIV cohorts to investigate long-term outcomes and improve the care of the next generation of children with HIV.

KW - Adolescent

KW - Adult

KW - Cohort Studies

KW - Europe

KW - Female

KW - HIV Infections

KW - Humans

KW - Infant, Newborn

KW - Infectious Disease Transmission, Vertical

KW - Surveys and Questionnaires

KW - Young Adult

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.2807/1560-7917.ES.2016.21.10.30162

DO - 10.2807/1560-7917.ES.2016.21.10.30162

M3 - Journal article

C2 - 26988197

VL - 21

JO - Eurosurveillance

JF - Eurosurveillance

SN - 1025-496X

IS - 10

M1 - 30162

ER -