Cardiac pulsatility mapping and vessel type identification using laser speckle contrast imaging
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Cardiac pulsatility mapping and vessel type identification using laser speckle contrast imaging. / Postnov, Dmitry D.; Erdener, Sefik Evren; Kilic, Kivilcim; Boas, David A.
I: Biomedical Optics Express, Bind 9, Nr. 12, 2018, s. 6388-6397.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › fagfællebedømt
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TY - JOUR
T1 - Cardiac pulsatility mapping and vessel type identification using laser speckle contrast imaging
AU - Postnov, Dmitry D.
AU - Erdener, Sefik Evren
AU - Kilic, Kivilcim
AU - Boas, David A.
PY - 2018
Y1 - 2018
N2 - Systemic flow variations caused by the cardiac cycle can play a role or be an important marker in both normal and pathological conditions. The shape, magnitude and propagation speed of the flow pulse reflect mechanical properties of the vasculature and are known to vary significantly with vascular diseases. Most conventional techniques are not capable of imaging cardiac activity in the microcirculation due to spatial and/or temporal resolution limitations and instead make inferences about propagation speed by making measurements at two points along an artery. Here, we apply laser speckle contrast imaging to images with high spatial resolution in the high frequency harmonics of cardiac activity in the cerebral cortex of a mouse. We reveal vessel dependent variation in the cardiac pulse activity and use this information to automatically identify arteries and veins. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
AB - Systemic flow variations caused by the cardiac cycle can play a role or be an important marker in both normal and pathological conditions. The shape, magnitude and propagation speed of the flow pulse reflect mechanical properties of the vasculature and are known to vary significantly with vascular diseases. Most conventional techniques are not capable of imaging cardiac activity in the microcirculation due to spatial and/or temporal resolution limitations and instead make inferences about propagation speed by making measurements at two points along an artery. Here, we apply laser speckle contrast imaging to images with high spatial resolution in the high frequency harmonics of cardiac activity in the cerebral cortex of a mouse. We reveal vessel dependent variation in the cardiac pulse activity and use this information to automatically identify arteries and veins. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
U2 - 10.1364/BOE.9.006388
DO - 10.1364/BOE.9.006388
M3 - Journal article
C2 - 31065436
VL - 9
SP - 6388
EP - 6397
JO - Biomedical Optics Express
JF - Biomedical Optics Express
SN - 2156-7085
IS - 12
ER -
ID: 210006510