Calpain 3 is important for muscle regeneration: evidence from patients with limb girdle muscular dystrophies
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › fagfællebedømt
Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this study was to investigate how mutations in the four functional domains of calpain 3 affect muscle regeneration.
|Tidsskrift||B M C Musculoskeletal Disorders|
|Status||Udgivet - 2012|