Borderline-positive quantiferon in children
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Borderline-positive quantiferon in children. / Nygaard, Ulrikka; Poulsen, Anja; Nielsen, Alex Yde; Ravn, Pernille; Vissing, Nadja Hawwa.
I: Pediatric Infectious Disease Journal, Bind 38, Nr. 11, 2019, s. E307-E309.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Borderline-positive quantiferon in children
AU - Nygaard, Ulrikka
AU - Poulsen, Anja
AU - Nielsen, Alex Yde
AU - Ravn, Pernille
AU - Vissing, Nadja Hawwa
PY - 2019
Y1 - 2019
N2 - We systematically retested children with borderline-positive quantiferon (0.35-0.99 IU/mL) during the period 2015-2019. Among 647 tests, 27 (4%) were positive (>0.35 IU/mL). Borderline-positive quantiferon accounted for 10 of 27 (37%) positive tests. When retested, 9 of 10 (90%) were negative. Children younger than 5 years had negative tuberculin skin tests. Thus, we found high test variability in the borderline range and, in some children, high suspicion of false positive tests.
AB - We systematically retested children with borderline-positive quantiferon (0.35-0.99 IU/mL) during the period 2015-2019. Among 647 tests, 27 (4%) were positive (>0.35 IU/mL). Borderline-positive quantiferon accounted for 10 of 27 (37%) positive tests. When retested, 9 of 10 (90%) were negative. Children younger than 5 years had negative tuberculin skin tests. Thus, we found high test variability in the borderline range and, in some children, high suspicion of false positive tests.
KW - Interferon gamma release assay
KW - Quantiferon
KW - Tuberculosis
U2 - 10.1097/INF.0000000000002416
DO - 10.1097/INF.0000000000002416
M3 - Journal article
C2 - 31306352
AN - SCOPUS:85073582781
VL - 38
SP - E307-E309
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
SN - 0891-3668
IS - 11
ER -
ID: 241371169