TY - JOUR

T1 - Association of summer temperatures and acute kidney injury in South Korea

T2 - a case-crossover study

AU - Ahn, Joonho

AU - Bae, Sanghyuk

AU - Ha Chung, Byung

AU - Myong, Jun-Pyo

AU - Park, Min Young

AU - Lim, Youn-Hee

AU - Kang, Mo-Yeol

PY - 2023

Y1 - 2023

N2 - Background Due to climate change, days with high temperatures are becoming more frequent. Although the effect of high temperature on the kidneys has been reported in research from Central and South America, Oceania, North America and Europe, evidence from Asia is still lacking. This study aimed to examine the association between short-term exposure to high temperatures and acute kidney injury (AKI) in a nationwide study in South Korea. Methods We used representative sampling data from the 2002-2015 National Health Insurance Service-National Sample Cohort in South Korea to link the daily mean temperatures and AKI cases that occurred in the summer. We used a bidirectional case-crossover study design with 0-7 lag days before the emergency room visit for AKI. In addition, we stratified the data into six income levels to identify the susceptible population. Results A total of 1706 participants were included in this study. The odds ratio (OR) per 1 degrees C increase at 0 lag days was 1.051, and the ORs per 1 degrees C increase at a lag of 2 days were both 1.076. The association between exposure to high temperatures and AKI was slightly greater in the low-income group (OR = 1.088; 95% CI: 1.049-1.128) than in the high-income group (OR = 1.065; 95% CI: 1.026-1.105). Conclusions In our study, a relationship between exposure to high temperatures and AKI was observed. Precautions should be taken at elevated temperatures to minimize the risk of negative health effects.

AB - Background Due to climate change, days with high temperatures are becoming more frequent. Although the effect of high temperature on the kidneys has been reported in research from Central and South America, Oceania, North America and Europe, evidence from Asia is still lacking. This study aimed to examine the association between short-term exposure to high temperatures and acute kidney injury (AKI) in a nationwide study in South Korea. Methods We used representative sampling data from the 2002-2015 National Health Insurance Service-National Sample Cohort in South Korea to link the daily mean temperatures and AKI cases that occurred in the summer. We used a bidirectional case-crossover study design with 0-7 lag days before the emergency room visit for AKI. In addition, we stratified the data into six income levels to identify the susceptible population. Results A total of 1706 participants were included in this study. The odds ratio (OR) per 1 degrees C increase at 0 lag days was 1.051, and the ORs per 1 degrees C increase at a lag of 2 days were both 1.076. The association between exposure to high temperatures and AKI was slightly greater in the low-income group (OR = 1.088; 95% CI: 1.049-1.128) than in the high-income group (OR = 1.065; 95% CI: 1.026-1.105). Conclusions In our study, a relationship between exposure to high temperatures and AKI was observed. Precautions should be taken at elevated temperatures to minimize the risk of negative health effects.

KW - Temperature

KW - acute kidney injury

KW - case-crossover study

KW - HOSPITAL ADMISSIONS

KW - HEAT WAVES

KW - PARTICULATE MATTER

KW - MORTALITY

KW - HEALTH

KW - RISK

KW - VULNERABILITY

KW - METAANALYSIS

KW - DEHYDRATION

KW - CLIMATE

U2 - 10.1093/ije/dyac163

DO - 10.1093/ije/dyac163

M3 - Journal article

C2 - 35950799

VL - 52

SP - 774

EP - 782

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

SN - 0300-5771

IS - 3

ER -