Assessing health-related quality of life in patients with benign non-toxic goitre

Publikation: Bidrag til tidsskriftReviewfagfællebedømt

Health-related quality of life (HRQoL) assessments are increasingly used to evaluate treatment effects and to shape the delivery of value based care. Valid generic and disease specific tools are available for quantifying HRQoL in patients with non-toxic goitre. However, few studies have applied these validated instruments to assess HRQoL in patients with benign non-toxic goitre. Limited evidence suggests that patients with non-toxic goitre have HRQoL impairments in multiple HRQoL domains. While the HRQoL-impact of non-toxic goitre may be small relative to other severely disabling medical conditions, treatment is almost exclusively elected for HRQoL indications. Thus better quantification of HRQoL, particularly at better (or more favorable) levels where many patients score, is essential. Web and mobile technologies have eased the ability to deliver surveys to patients. Routine consideration of HRQoL provides the opportunity to monitor the impact of treatment on the outcomes most meaningful for patients and the opportunity to help shape the delivery of value based health care.

TidsskriftBest Practice and Research: Clinical Endocrinology and Metabolism
Udgave nummer4
Sider (fra-til)559-575
Antal sider17
StatusUdgivet - aug. 2014

Bibliografisk note

Funding Information:
We would like to thank Mikel Strom, MSLIS, for helping to design and perform the literature search for this systematic review. This work was supported by the Danish Agency for Science, Technology and Innovation (grant 271-09-0143 ) and the Danish Council for Independent Research (grant 09-066886 ). L.H. is supported by an unrestricted research grant from the Novo Nordisk Foundation , and U.F.-R. from Arvid Nilsson's Fund . S.J.B. is supported by an unrestricted research grant from The Research Council at Odense University Hospital .

ID: 303679272