Analysis of antibody inhibition of PfEMP1 binding by competition ELISA
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
Plasmodium falciparum express variant antigens on the surface of infected erythrocytes (IEs). These include proteins of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family. PfEMP1 proteins mediate binding of IEs to various human endothelial receptors and induce antibodies response during natural infections. In this chapter, we describe a competition ELISA that is an assay for antibodies neutralizing binding of PfEMP1 proteins to their cognate receptor.
Originalsprog | Engelsk |
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Titel | Malaria Immunology : Targeting the Surface of Infected Erythrocytes |
Antal sider | 7 |
Vol/bind | 2470 |
Forlag | Humana Press |
Publikationsdato | 2022 |
Sider | 485-491 |
ISBN (Elektronisk) | 978-1-0716-2189-9 |
DOI | |
Status | Udgivet - 2022 |
Navn | Methods in molecular biology (Clifton, N.J.) |
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ISSN | 1064-3745 |
Bibliografisk note
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
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