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An Aboriginal Australian genome reveals separate human dispersals into Asia. / Rasmussen, Morten; Guo, Xiaosen; Wang, Yong; Lohmueller, Kirk E.; Rasmussen, Simon; Albrechtsen, Anders; Skotte, Line; Lindgreen, Stinus; Metspalu, Mait; Jombart, Thibaut; Kivisild, Toomas; Zhai, Weiwei; Eriksson, Anders; Manica, Andrea; Orlando, Ludovic; De La Vega, Francisco M.; Tridico, Silvana; Metspalu, Ene; Nielsen, Kasper; Avila Arcos, Maria del Carmen; Moreno Mayar, José Victor; Muller, Craig; Dortch, Joe; Gilbert, Tom; Lund, Ole; Wesolowska, Agata; Karmin, Monika; Weinert, Lucy A.; Wang, Bo; Li, Jun; Tai, Shuaishuai; Xiao, Fei; Hanihara, Tsunehiko; van Driem, George; Jha, Aashish R.; Ricaut, François-Xavier; de Knijff, Peter; Migliano, Andrea B.; Gallego Romero, Irene; Kristiansen, Karsten; Lambert, David M.; Brunak, Søren; Forster, Peter; Brinkmann, Bernd; Nehlich, Olaf; Bunce, Michael; Richards, Michael; Gupta, Ramneek; Bustamante, Carlos D.; Krogh, Anders; Foley, Robert A.; Lahr, Marta M.; Balloux, Francois; Sicheritz-Pontén, Thomas; Villems, Richard; Nielsen, Rasmus; Wang, Jun; Willerslev, Eske.
I:
Science, Bind 334, Nr. 6052, 2011, s. 94-98.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Rasmussen, M, Guo, X, Wang, Y, Lohmueller, KE
, Rasmussen, S, Albrechtsen, A, Skotte, L, Lindgreen, S, Metspalu, M, Jombart, T, Kivisild, T, Zhai, W, Eriksson, A, Manica, A, Orlando, L, De La Vega, FM, Tridico, S, Metspalu, E, Nielsen, K, Avila Arcos, MDC
, Moreno Mayar, JV, Muller, C, Dortch, J
, Gilbert, T, Lund, O, Wesolowska, A, Karmin, M, Weinert, LA, Wang, B, Li, J, Tai, S, Xiao, F, Hanihara, T, van Driem, G, Jha, AR, Ricaut, F-X, de Knijff, P, Migliano, AB, Gallego Romero, I
, Kristiansen, K, Lambert, DM
, Brunak, S, Forster, P, Brinkmann, B, Nehlich, O, Bunce, M, Richards, M, Gupta, R, Bustamante, CD
, Krogh, A, Foley, RA, Lahr, MM, Balloux, F, Sicheritz-Pontén, T, Villems, R
, Nielsen, R, Wang, J
& Willerslev, E 2011, '
An Aboriginal Australian genome reveals separate human dispersals into Asia',
Science, bind 334, nr. 6052, s. 94-98.
https://doi.org/10.1126/science.1211177APA
Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E.
, Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K.
, ... Willerslev, E. (2011).
An Aboriginal Australian genome reveals separate human dispersals into Asia.
Science,
334(6052), 94-98.
https://doi.org/10.1126/science.1211177Vancouver
Rasmussen M, Guo X, Wang Y, Lohmueller KE
, Rasmussen S, Albrechtsen A o.a.
An Aboriginal Australian genome reveals separate human dispersals into Asia.
Science. 2011;334(6052):94-98.
https://doi.org/10.1126/science.1211177Author
Rasmussen, Morten ; Guo, Xiaosen ; Wang, Yong ; Lohmueller, Kirk E. ; Rasmussen, Simon ; Albrechtsen, Anders ; Skotte, Line ; Lindgreen, Stinus ; Metspalu, Mait ; Jombart, Thibaut ; Kivisild, Toomas ; Zhai, Weiwei ; Eriksson, Anders ; Manica, Andrea ; Orlando, Ludovic ; De La Vega, Francisco M. ; Tridico, Silvana ; Metspalu, Ene ; Nielsen, Kasper ; Avila Arcos, Maria del Carmen ; Moreno Mayar, José Victor ; Muller, Craig ; Dortch, Joe ; Gilbert, Tom ; Lund, Ole ; Wesolowska, Agata ; Karmin, Monika ; Weinert, Lucy A. ; Wang, Bo ; Li, Jun ; Tai, Shuaishuai ; Xiao, Fei ; Hanihara, Tsunehiko ; van Driem, George ; Jha, Aashish R. ; Ricaut, François-Xavier ; de Knijff, Peter ; Migliano, Andrea B. ; Gallego Romero, Irene ; Kristiansen, Karsten ; Lambert, David M. ; Brunak, Søren ; Forster, Peter ; Brinkmann, Bernd ; Nehlich, Olaf ; Bunce, Michael ; Richards, Michael ; Gupta, Ramneek ; Bustamante, Carlos D. ; Krogh, Anders ; Foley, Robert A. ; Lahr, Marta M. ; Balloux, Francois ; Sicheritz-Pontén, Thomas ; Villems, Richard ; Nielsen, Rasmus ; Wang, Jun ; Willerslev, Eske. / An Aboriginal Australian genome reveals separate human dispersals into Asia. I: Science. 2011 ; Bind 334, Nr. 6052. s. 94-98.
Bibtex
@article{dc293b134cbb4eee8adab4d958e81ddf,
title = "An Aboriginal Australian genome reveals separate human dispersals into Asia",
abstract = "We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.",
keywords = "African Continental Ancestry Group, Animals, Asia, Asian Continental Ancestry Group, Computer Simulation, DNA, Mitochondrial, Emigration and Immigration, Ethnic Groups, European Continental Ancestry Group, Far East, Gene Flow, Gene Frequency, Genetics, Population, Genome, Human, Genome, Mitochondrial, Haplotypes, Hominidae, Humans, Linkage Disequilibrium, Male, Oceanic Ancestry Group, Phylogeny, Polymorphism, Single Nucleotide, Sequence Analysis, DNA, Western Australia",
author = "Morten Rasmussen and Xiaosen Guo and Yong Wang and Lohmueller, {Kirk E.} and Simon Rasmussen and Anders Albrechtsen and Line Skotte and Stinus Lindgreen and Mait Metspalu and Thibaut Jombart and Toomas Kivisild and Weiwei Zhai and Anders Eriksson and Andrea Manica and Ludovic Orlando and {De La Vega}, {Francisco M.} and Silvana Tridico and Ene Metspalu and Kasper Nielsen and {Avila Arcos}, {Maria del Carmen} and {Moreno Mayar}, {Jos{\'e} Victor} and Craig Muller and Joe Dortch and Tom Gilbert and Ole Lund and Agata Wesolowska and Monika Karmin and Weinert, {Lucy A.} and Bo Wang and Jun Li and Shuaishuai Tai and Fei Xiao and Tsunehiko Hanihara and {van Driem}, George and Jha, {Aashish R.} and Fran{\c c}ois-Xavier Ricaut and {de Knijff}, Peter and Migliano, {Andrea B.} and {Gallego Romero}, Irene and Karsten Kristiansen and Lambert, {David M.} and S{\o}ren Brunak and Peter Forster and Bernd Brinkmann and Olaf Nehlich and Michael Bunce and Michael Richards and Ramneek Gupta and Bustamante, {Carlos D.} and Anders Krogh and Foley, {Robert A.} and Lahr, {Marta M.} and Francois Balloux and Thomas Sicheritz-Pont{\'e}n and Richard Villems and Rasmus Nielsen and Jun Wang and Eske Willerslev",
year = "2011",
doi = "10.1126/science.1211177",
language = "English",
volume = "334",
pages = "94--98",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "6052",
}
RIS
TY - JOUR
T1 - An Aboriginal Australian genome reveals separate human dispersals into Asia
AU - Rasmussen, Morten
AU - Guo, Xiaosen
AU - Wang, Yong
AU - Lohmueller, Kirk E.
AU - Rasmussen, Simon
AU - Albrechtsen, Anders
AU - Skotte, Line
AU - Lindgreen, Stinus
AU - Metspalu, Mait
AU - Jombart, Thibaut
AU - Kivisild, Toomas
AU - Zhai, Weiwei
AU - Eriksson, Anders
AU - Manica, Andrea
AU - Orlando, Ludovic
AU - De La Vega, Francisco M.
AU - Tridico, Silvana
AU - Metspalu, Ene
AU - Nielsen, Kasper
AU - Avila Arcos, Maria del Carmen
AU - Moreno Mayar, José Victor
AU - Muller, Craig
AU - Dortch, Joe
AU - Gilbert, Tom
AU - Lund, Ole
AU - Wesolowska, Agata
AU - Karmin, Monika
AU - Weinert, Lucy A.
AU - Wang, Bo
AU - Li, Jun
AU - Tai, Shuaishuai
AU - Xiao, Fei
AU - Hanihara, Tsunehiko
AU - van Driem, George
AU - Jha, Aashish R.
AU - Ricaut, François-Xavier
AU - de Knijff, Peter
AU - Migliano, Andrea B.
AU - Gallego Romero, Irene
AU - Kristiansen, Karsten
AU - Lambert, David M.
AU - Brunak, Søren
AU - Forster, Peter
AU - Brinkmann, Bernd
AU - Nehlich, Olaf
AU - Bunce, Michael
AU - Richards, Michael
AU - Gupta, Ramneek
AU - Bustamante, Carlos D.
AU - Krogh, Anders
AU - Foley, Robert A.
AU - Lahr, Marta M.
AU - Balloux, Francois
AU - Sicheritz-Pontén, Thomas
AU - Villems, Richard
AU - Nielsen, Rasmus
AU - Wang, Jun
AU - Willerslev, Eske
PY - 2011
Y1 - 2011
N2 - We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.
AB - We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.
KW - African Continental Ancestry Group
KW - Animals
KW - Asia
KW - Asian Continental Ancestry Group
KW - Computer Simulation
KW - DNA, Mitochondrial
KW - Emigration and Immigration
KW - Ethnic Groups
KW - European Continental Ancestry Group
KW - Far East
KW - Gene Flow
KW - Gene Frequency
KW - Genetics, Population
KW - Genome, Human
KW - Genome, Mitochondrial
KW - Haplotypes
KW - Hominidae
KW - Humans
KW - Linkage Disequilibrium
KW - Male
KW - Oceanic Ancestry Group
KW - Phylogeny
KW - Polymorphism, Single Nucleotide
KW - Sequence Analysis, DNA
KW - Western Australia
U2 - 10.1126/science.1211177
DO - 10.1126/science.1211177
M3 - Journal article
C2 - 21940856
VL - 334
SP - 94
EP - 98
JO - Science
JF - Science
SN - 0036-8075
IS - 6052
ER -
