Amphipols from A to Z

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Amphipols from A to Z. / Popot, J-L; Althoff, T; Bagnard, D; Banères, J-L; Bazzacco, P; Billon-Denis, E; Catoire, Laurent J. ; Champeil, P; Charvolin, D; Cocco, M J; Crémel, G; Dahmane, T; de la Maza, L M; Ebel, C; Gabel, F; Giusti, F; Gohon, Y; Goormaghtigh, E; Guittet, E; Kleinschmidt, J. H. ; Kühlbrandt, W; Le Bon, C; Martinez, Karen Laurence; Picard, M; Pucci, B; Sachs, J N ; Tribet, C; Van Heijenoort, C; Wien, F; Zito, F; Zoonens, M.

I: Annual Review of Biophysics, Bind 40, 06.2011, s. 379-408.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Popot, J-L, Althoff, T, Bagnard, D, Banères, J-L, Bazzacco, P, Billon-Denis, E, Catoire, LJ, Champeil, P, Charvolin, D, Cocco, MJ, Crémel, G, Dahmane, T, de la Maza, LM, Ebel, C, Gabel, F, Giusti, F, Gohon, Y, Goormaghtigh, E, Guittet, E, Kleinschmidt, JH, Kühlbrandt, W, Le Bon, C, Martinez, KL, Picard, M, Pucci, B, Sachs, JN, Tribet, C, Van Heijenoort, C, Wien, F, Zito, F & Zoonens, M 2011, 'Amphipols from A to Z', Annual Review of Biophysics, bind 40, s. 379-408. https://doi.org/10.1146/annurev-biophys-042910-155219

APA

Popot, J-L., Althoff, T., Bagnard, D., Banères, J-L., Bazzacco, P., Billon-Denis, E., Catoire, L. J., Champeil, P., Charvolin, D., Cocco, M. J., Crémel, G., Dahmane, T., de la Maza, L. M., Ebel, C., Gabel, F., Giusti, F., Gohon, Y., Goormaghtigh, E., Guittet, E., ... Zoonens, M. (2011). Amphipols from A to Z. Annual Review of Biophysics, 40, 379-408. https://doi.org/10.1146/annurev-biophys-042910-155219

Vancouver

Popot J-L, Althoff T, Bagnard D, Banères J-L, Bazzacco P, Billon-Denis E o.a. Amphipols from A to Z. Annual Review of Biophysics. 2011 jun.;40:379-408. https://doi.org/10.1146/annurev-biophys-042910-155219

Author

Popot, J-L ; Althoff, T ; Bagnard, D ; Banères, J-L ; Bazzacco, P ; Billon-Denis, E ; Catoire, Laurent J. ; Champeil, P ; Charvolin, D ; Cocco, M J ; Crémel, G ; Dahmane, T ; de la Maza, L M ; Ebel, C ; Gabel, F ; Giusti, F ; Gohon, Y ; Goormaghtigh, E ; Guittet, E ; Kleinschmidt, J. H. ; Kühlbrandt, W ; Le Bon, C ; Martinez, Karen Laurence ; Picard, M ; Pucci, B ; Sachs, J N ; Tribet, C ; Van Heijenoort, C ; Wien, F ; Zito, F ; Zoonens, M. / Amphipols from A to Z. I: Annual Review of Biophysics. 2011 ; Bind 40. s. 379-408.

Bibtex

@article{d0de6477b9f543d0bd0e60e29f755644,
title = "Amphipols from A to Z",
abstract = "Amphipols (APols) are short amphipathic polymers that can substitute for detergents to keep integral membrane proteins (MPs) water soluble. In this review, we discuss their structure and solution behavior; the way they associate with MPs; and the structure, dynamics, and solution properties of the resulting complexes. All MPs tested to date form water-soluble complexes with APols, and their biochemical stability is in general greatly improved compared with MPs in detergent solutions. The functionality and ligand-binding properties of APol-trapped MPs are reviewed, and the mechanisms by which APols stabilize MPs are discussed. Applications of APols include MP folding and cell-free synthesis, structural studies by NMR, electron microscopy and X-ray diffraction, APol-mediated immobilization of MPs onto solid supports, proteomics, delivery of MPs to preexisting membranes, and vaccine formulation.",
author = "J-L Popot and T Althoff and D Bagnard and J-L Ban{\`e}res and P Bazzacco and E Billon-Denis and Catoire, {Laurent J.} and P Champeil and D Charvolin and Cocco, {M J} and G Cr{\'e}mel and T Dahmane and {de la Maza}, {L M} and C Ebel and F Gabel and F Giusti and Y Gohon and E Goormaghtigh and E Guittet and Kleinschmidt, {J. H.} and W K{\"u}hlbrandt and {Le Bon}, C and Martinez, {Karen Laurence} and M Picard and B Pucci and Sachs, {J N} and C Tribet and {Van Heijenoort}, C and F Wien and F Zito and M Zoonens",
year = "2011",
month = jun,
doi = "10.1146/annurev-biophys-042910-155219",
language = "English",
volume = "40",
pages = "379--408",
journal = "Annual Review of Biophysics",
issn = "1936-122X",
publisher = "Annual Reviews, inc.",

}

RIS

TY - JOUR

T1 - Amphipols from A to Z

AU - Popot, J-L

AU - Althoff, T

AU - Bagnard, D

AU - Banères, J-L

AU - Bazzacco, P

AU - Billon-Denis, E

AU - Catoire, Laurent J.

AU - Champeil, P

AU - Charvolin, D

AU - Cocco, M J

AU - Crémel, G

AU - Dahmane, T

AU - de la Maza, L M

AU - Ebel, C

AU - Gabel, F

AU - Giusti, F

AU - Gohon, Y

AU - Goormaghtigh, E

AU - Guittet, E

AU - Kleinschmidt, J. H.

AU - Kühlbrandt, W

AU - Le Bon, C

AU - Martinez, Karen Laurence

AU - Picard, M

AU - Pucci, B

AU - Sachs, J N

AU - Tribet, C

AU - Van Heijenoort, C

AU - Wien, F

AU - Zito, F

AU - Zoonens, M

PY - 2011/6

Y1 - 2011/6

N2 - Amphipols (APols) are short amphipathic polymers that can substitute for detergents to keep integral membrane proteins (MPs) water soluble. In this review, we discuss their structure and solution behavior; the way they associate with MPs; and the structure, dynamics, and solution properties of the resulting complexes. All MPs tested to date form water-soluble complexes with APols, and their biochemical stability is in general greatly improved compared with MPs in detergent solutions. The functionality and ligand-binding properties of APol-trapped MPs are reviewed, and the mechanisms by which APols stabilize MPs are discussed. Applications of APols include MP folding and cell-free synthesis, structural studies by NMR, electron microscopy and X-ray diffraction, APol-mediated immobilization of MPs onto solid supports, proteomics, delivery of MPs to preexisting membranes, and vaccine formulation.

AB - Amphipols (APols) are short amphipathic polymers that can substitute for detergents to keep integral membrane proteins (MPs) water soluble. In this review, we discuss their structure and solution behavior; the way they associate with MPs; and the structure, dynamics, and solution properties of the resulting complexes. All MPs tested to date form water-soluble complexes with APols, and their biochemical stability is in general greatly improved compared with MPs in detergent solutions. The functionality and ligand-binding properties of APol-trapped MPs are reviewed, and the mechanisms by which APols stabilize MPs are discussed. Applications of APols include MP folding and cell-free synthesis, structural studies by NMR, electron microscopy and X-ray diffraction, APol-mediated immobilization of MPs onto solid supports, proteomics, delivery of MPs to preexisting membranes, and vaccine formulation.

U2 - 10.1146/annurev-biophys-042910-155219

DO - 10.1146/annurev-biophys-042910-155219

M3 - Journal article

C2 - 21545287

VL - 40

SP - 379

EP - 408

JO - Annual Review of Biophysics

JF - Annual Review of Biophysics

SN - 1936-122X

ER -

ID: 33826425