Adherence to preventive statin therapy according to socioeconomic position
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Adherence to preventive statin therapy according to socioeconomic position. / Wallach-Kildemoes, Helle ; Andersen, Morten; Diderichsen, Finn; Lange, Theis.
I: European Journal of Clinical Pharmacology, Bind 69, Nr. 8, 08.2013, s. 1553-1563.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Adherence to preventive statin therapy according to socioeconomic position
AU - Wallach-Kildemoes, Helle
AU - Andersen, Morten
AU - Diderichsen, Finn
AU - Lange, Theis
PY - 2013/8
Y1 - 2013/8
N2 - AIM: To explore whether long-term adherence to preventive statin therapy depends on socioeconomic position (SEP). METHODS: A cohort of individuals without established cardiovascular disease (CVD) or diabetes initiating preventive statin therapy during 2002-2005 was followed in the individual-level Danish registries for 4 years or until censoring events (death, emigration, CVD or diabetes). Only individuals aged 40-84 years for whom information was available on the SEP indicators, education and income were included (N = 76,038). Two different aspects of poor adherence were applied as outcome measures: (1) Proportion of days covered (PDC) with medication below 80 %, assuming a daily dose of one tablet (continuity); (2) Discontinuation defined as a gap between two consecutive prescriptions exceeding 365 days (persistence). Stratum-specific logistic regression analyses were applied to estimate the odds ratio (OR) for PDC
AB - AIM: To explore whether long-term adherence to preventive statin therapy depends on socioeconomic position (SEP). METHODS: A cohort of individuals without established cardiovascular disease (CVD) or diabetes initiating preventive statin therapy during 2002-2005 was followed in the individual-level Danish registries for 4 years or until censoring events (death, emigration, CVD or diabetes). Only individuals aged 40-84 years for whom information was available on the SEP indicators, education and income were included (N = 76,038). Two different aspects of poor adherence were applied as outcome measures: (1) Proportion of days covered (PDC) with medication below 80 %, assuming a daily dose of one tablet (continuity); (2) Discontinuation defined as a gap between two consecutive prescriptions exceeding 365 days (persistence). Stratum-specific logistic regression analyses were applied to estimate the odds ratio (OR) for PDC
U2 - 10.1007/s00228-013-1488-6
DO - 10.1007/s00228-013-1488-6
M3 - Journal article
C2 - 23588558
VL - 69
SP - 1553
EP - 1563
JO - European Journal of Clinical Pharmacology
JF - European Journal of Clinical Pharmacology
SN - 0031-6970
IS - 8
ER -
ID: 45664308