A systematic review of studies on psychosocial late effects of childhood cancer: structures of society and methodological pitfalls may challenge the conclusions
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A systematic review of studies on psychosocial late effects of childhood cancer: structures of society and methodological pitfalls may challenge the conclusions. / Lund, Lasse Wegener; Schmiegelow, Kjeld; Rechnitzer, Catherine; Johansen, Christoffer.
I: Pediatric Blood & Cancer, Bind 56, Nr. 4, 01.04.2011, s. 532-43.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - A systematic review of studies on psychosocial late effects of childhood cancer: structures of society and methodological pitfalls may challenge the conclusions
AU - Lund, Lasse Wegener
AU - Schmiegelow, Kjeld
AU - Rechnitzer, Catherine
AU - Johansen, Christoffer
N1 - epub ahead of print i 2010
PY - 2011/4/1
Y1 - 2011/4/1
N2 - High survival rates after childhood cancer raise attention to possible psychosocial late effects. We focus on predictors of psychosocial outcomes based on diagnosis, treatment, demography, somatic disease, and methodological problems. Overall, survivors evaluate their health-related quality of life to be normal or even better than controls, although virtually all diagnostic subgroups report psychosocial impairment. Central nervous system tumor survivors have significant psychosocial problems. Negative outcomes were associated with cranial radiation therapy, female gender, and young age at diagnosis. Significant methodological problems hamper current knowledge. Systematic registration of psychosocial and somatic problems at diagnosis and prospectively through protocols is needed. Pediatr Blood Cancer © 2010 Wiley-Liss, Inc.
AB - High survival rates after childhood cancer raise attention to possible psychosocial late effects. We focus on predictors of psychosocial outcomes based on diagnosis, treatment, demography, somatic disease, and methodological problems. Overall, survivors evaluate their health-related quality of life to be normal or even better than controls, although virtually all diagnostic subgroups report psychosocial impairment. Central nervous system tumor survivors have significant psychosocial problems. Negative outcomes were associated with cranial radiation therapy, female gender, and young age at diagnosis. Significant methodological problems hamper current knowledge. Systematic registration of psychosocial and somatic problems at diagnosis and prospectively through protocols is needed. Pediatr Blood Cancer © 2010 Wiley-Liss, Inc.
U2 - http://dx.doi.org/10.1002/pbc.22883
DO - http://dx.doi.org/10.1002/pbc.22883
M3 - Journal article
VL - 56
SP - 532
EP - 543
JO - Pediatric Blood & Cancer
JF - Pediatric Blood & Cancer
SN - 1545-5009
IS - 4
ER -
ID: 34155386