A national repository of complete radiotherapy plans: design, Results, and experiences

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Simon Long Krogh
  • Carsten Brink
  • Ebbe Laugaard Lorenzen
  • Eva Samsøe
  • Vogelius, Ivan
  • Ruta Zukauskaite
  • Birgitte Vrou Offersen
  • Jesper Grau Eriksen
  • Olfred Hansen
  • Jørgen Johansen
  • Agon Olloni
  • Christina H. Ruhlmann
  • Lone Hoffmann
  • Henrik Dahl Nissen
  • Martin Skovmos Nielsen
  • Karen Andersen
  • Cai Grau
  • Christian Rønn Hansen
Background
Previously, many radiotherapy (RT) trials were based on a few selected dose measures. Many research questions, however, rely on access to the complete dose information. To support such access, a national RT plan database was created. The system focuses on data security, ease of use, and re-use of data. This article reports on the development and structure, and the functionality and experience of this national database.

Methods and materials
A system based on the DICOM-RT standard, DcmCollab, was implemented with direct connections to all Danish RT centres. Data is segregated into any number of collaboration projects. User access to the system is provided through a web interface. The database has a finely defined access permission model to support legal requirements.

Results
Currently, data for more than 14,000 patients have been submitted to the system, and more than 50 research projects are registered. The system is used for data collection, trial quality assurance, and audit data set generation.

Users reported that the process of submitting data, waiting for it to be processed, and then manually attaching it to a project was resource intensive. This was accommodated with the introduction of triggering features, eliminating much of the need for users to manage data manually. Many other features, including structure name mapping, RT plan viewer, and the Audit Tool were developed based on user input.

Conclusion
The DcmCollab system has provided an efficient means to collect and access complete datasets for multi-centre RT research. This stands in contrast with previous methods of collecting RT data in multi-centre settings, where only singular data points were manually reported. To accommodate the evolving legal environment, DcmCollab has been defined as a ‘data processor’, meaning that it is a tool for other research projects to use rather than a research project in and of itself.
OriginalsprogEngelsk
TidsskriftActa Oncologica
Vol/bind62
Udgave nummer10
Sider (fra-til)1161-1168
Antal sider8
ISSN0284-186X
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
This work was funded by the Lundbeck Foundation Centre for Interventional Research in Radiation Oncology (CIRRO), The Danish Cancer Society (DCCC Radiotherapy), the Danish Medical Research Council and the Novo Nordisk Foundation.

Publisher Copyright:
© 2023 Acta Oncologica Foundation.

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