Peter E. Nielsen

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Primære forskningsområder

The research interests are centered around the DNA mimic PNA (peptide nucleic acid), and the chemical biology and medicinal chemistry properties and applications of derivatives of this molecule. This includes drug discovery (antisense antibiotics, muscular dystrophy, cystic fibrosis), gene targeting and antisense principles in general and cellular and in vivo delivery and administration of biopharmaceuticals. Additional interests cover origin of life prebiotic systems and the effects of oxidative stress on cellular RNA.

Aktuel forskning

• Discovery of PNA and peptide based antibiotics against resistant Gram-negative bacterial infections
• Quorum sensing inhibitors as cystic fibrosis drugs
• Antisense drugs for Duchenne muscular dystrophy
• Antisense drug delivery and in vivo administration

Mulige interessekonflikter

Member of the board of directors for Select Sport a/s, Copenhagen. 

Member of Scientific Advisory Board for Neubase Inc. Pennsylvania, USA.