Marie Louise Mølgaard Binderup
Medical Genetics Program
In my current postdoc pilot projekt "Drivers of hypoxia-induced angiogenesis in tumor development", I aim to elucidate hypoxia-induced angiogenesis in tumor development using central nervous system (CNS) hemangioblastoma tumorgenesis as a model.
I will identify genetic drivers of CNS hemangioblastoma progression and associated cyst development using genome-wide Next-Generation-Sequencing (NGS) and copy number profiling of tumor DNA paired with clinical information about each tumor’s growth pattern. The purpose is to look for recurrent mutations across tumors to identify common genetic mechanisms involved in early tumorigenesis.