Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades. To assess whether this pathway is causally relevant to coronary heart disease, we studied a functional genetic variant known to affect IL6R signalling.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Lancet |
Vol/bind | 379 |
Udgave nummer | 9822 |
Sider (fra-til) | 1205-13 |
Antal sider | 9 |
ISSN | 0140-6736 |
DOI | |
Status | Udgivet - 31 mar. 2012 |
ID: 46405461