Heparininduceret trombocytopeni
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Heparininduceret trombocytopeni. / Christoffersen, Christina; Lethagen, Stefan; Gøtze, Jens Peter.
I: Ugeskrift for Laeger, Bind 171, Nr. 8, 16.02.2009, s. 612-5.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning
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TY - JOUR
T1 - Heparininduceret trombocytopeni
AU - Christoffersen, Christina
AU - Lethagen, Stefan
AU - Gøtze, Jens Peter
PY - 2009/2/16
Y1 - 2009/2/16
N2 - Heparin treatment can cause an immune-mediated thrombocytopenia: HIT. HIT antibodies can be detected by various methods, but laboratory analyses are not specific or sensitive and may delay the diagnostic process. It is therefore important to initiate alternative treatment based on the clinical findings, and a clinical score system for evaluating the risk of HIT has been suggested. When HIT is likely, treatment consists of immediate replacement of heparin with alternative anticoagulation treatment and refrainment from warfarin therapy and platelet infusion.
AB - Heparin treatment can cause an immune-mediated thrombocytopenia: HIT. HIT antibodies can be detected by various methods, but laboratory analyses are not specific or sensitive and may delay the diagnostic process. It is therefore important to initiate alternative treatment based on the clinical findings, and a clinical score system for evaluating the risk of HIT has been suggested. When HIT is likely, treatment consists of immediate replacement of heparin with alternative anticoagulation treatment and refrainment from warfarin therapy and platelet infusion.
KW - Anticoagulants
KW - Chondroitin Sulfates
KW - Dermatan Sulfate
KW - Fibrinolytic Agents
KW - Heparin
KW - Heparitin Sulfate
KW - Hirudins
KW - Humans
KW - Pipecolic Acids
KW - Recombinant Proteins
KW - Risk Factors
KW - Thrombocytopenia
M3 - Tidsskriftartikel
C2 - 19284907
VL - 171
SP - 612
EP - 615
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 8
ER -
ID: 100888331