Electroconvulsive Therapy and Risk of Road Traffic Accidents: A Danish Register-Based Cohort Study
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Electroconvulsive Therapy and Risk of Road Traffic Accidents : A Danish Register-Based Cohort Study. / Hjerrild, Simon; Jørgensen, Martin Balslev; Dam, Ole Henrik; Tehrani, Elisabeth; Videbech, Poul; Osler, Merete.
I: Journal of ECT, Bind 39, Nr. 1, 2023, s. 10-14.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Electroconvulsive Therapy and Risk of Road Traffic Accidents
T2 - A Danish Register-Based Cohort Study
AU - Hjerrild, Simon
AU - Jørgensen, Martin Balslev
AU - Dam, Ole Henrik
AU - Tehrani, Elisabeth
AU - Videbech, Poul
AU - Osler, Merete
N1 - Publisher Copyright: Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Objective The aim of the study is to examine whether electroconvulsive therapy (ECT) was associated with the subsequent risk of being involved in a road traffic accident. Methods A cohort of all 375,435 patients older than 18 years with their first psychiatric hospital contact between 2003 and 2017 in the Danish National Patient Registry was followed for road traffic accidents until December 2018. Associations between ECT and road traffic accidents were examined using Cox regression analyses with multiple adjustments and using propensity score matching on sociodemographic and clinical variables. Results A total of 8486 patients (0.2%) were treated with ECT. During the median follow-up of 5.9 years, 778 of these patients (12.5%) were involved in a road traffic accident and the unadjusted incidence of road traffic accidents was lower among these patients (incidence rate, 15.5 per 1000 patient-years; 95% confidence interval [CI], 14.5-16.7) compared with patients not treated with ECT (incidence rate, 20.0 per 1000 patient-years; 95% CI, 20.0-20.3). Electroconvulsive therapy was not associated with road traffic accidents in the Cox regression models after adjustment for all covariables (hazard ratio, 1.00; 95% CI, 0.92-1.08) or in the propensity score-matched sample (hazard ratio, 0.91; 95% CI, 0.83-1.08). The HRs did not vary materially with follow-up time or when analyses were stratified on sex, age, or type of hospital contact. Conclusions The analysis of Danish National registry data indicates that ECT is not associated with the risk of being involved in major road traffic accidents.
AB - Objective The aim of the study is to examine whether electroconvulsive therapy (ECT) was associated with the subsequent risk of being involved in a road traffic accident. Methods A cohort of all 375,435 patients older than 18 years with their first psychiatric hospital contact between 2003 and 2017 in the Danish National Patient Registry was followed for road traffic accidents until December 2018. Associations between ECT and road traffic accidents were examined using Cox regression analyses with multiple adjustments and using propensity score matching on sociodemographic and clinical variables. Results A total of 8486 patients (0.2%) were treated with ECT. During the median follow-up of 5.9 years, 778 of these patients (12.5%) were involved in a road traffic accident and the unadjusted incidence of road traffic accidents was lower among these patients (incidence rate, 15.5 per 1000 patient-years; 95% confidence interval [CI], 14.5-16.7) compared with patients not treated with ECT (incidence rate, 20.0 per 1000 patient-years; 95% CI, 20.0-20.3). Electroconvulsive therapy was not associated with road traffic accidents in the Cox regression models after adjustment for all covariables (hazard ratio, 1.00; 95% CI, 0.92-1.08) or in the propensity score-matched sample (hazard ratio, 0.91; 95% CI, 0.83-1.08). The HRs did not vary materially with follow-up time or when analyses were stratified on sex, age, or type of hospital contact. Conclusions The analysis of Danish National registry data indicates that ECT is not associated with the risk of being involved in major road traffic accidents.
KW - accidents
KW - depression
KW - driving
KW - ECT
KW - electroconvulsive therapy
KW - epidemiology
KW - major depression
KW - safety
KW - traffic accidents
U2 - 10.1097/YCT.0000000000000881
DO - 10.1097/YCT.0000000000000881
M3 - Journal article
C2 - 36095094
AN - SCOPUS:85148964623
VL - 39
SP - 10
EP - 14
JO - Journal of Electroconvulsive Therapy
JF - Journal of Electroconvulsive Therapy
SN - 1095-0680
IS - 1
ER -
ID: 339838746