Matrix metalloproteinase-8 overexpression prevents proper tissue repair

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Patricia L Danielsen, Anders V Holst, Henrik R Maltesen, Maria R Bassi, Peter J Holst, Katja M Heinemeier, Jørgen Olsen, Carl Christian Danielsen, Steen S Poulsen, Lars N Jorgensen, Magnus S Agren

The collagenolytic matrix metalloproteinase-8 (MMP-8) is essential for normal tissue repair but is often overexpressed in wounds with disrupted healing. Our aim was to study the impact of a local excess of this neutrophil-derived proteinase on wound healing using recombinant adenovirus-driven transduction of full-length Mmp8 (AdMMP-8).
OriginalsprogEngelsk
TidsskriftSurgery
Vol/bind150
Tidsskriftsnummer5
Sider (fra-til)897-906
Antal sider10
ISSN0263-9319
DOI
StatusUdgivet - 2011

ID: 35261469