Bisoprolol for congestive heart failure

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

J. Rosenberg, F. Gustafsson

Background: beta-Blockers are a cornerstone in the treatment of systolic heart failure treatment, but not all beta-blockers are effective or in this setting. Objective: To define the role of bisoprolol, a highly selective beta(1)-antagonist in congestive heart failure due to systolic dysfunction. Methods: Using the keywords 'bisoprolol' and 'heart failure' PubMed and BIOSIS databases were searched for information regarding pharmacology and relevant randomised clinical trials. Supplementary publications were acquired by scrutinising reference lists of relevant papers. Additional information was obtained from the FDA website. Conclusion: Bisoprolol is an effective and well-tolerated first-line beta-blocker for patients with systolic heart failure. The knowledge is primarily based on study patients with moderate-to-severe heart failure from the three CIBIS trials
Udgivelsesdato: 2008/2
OriginalsprogEngelsk
TidsskriftExpert Opinion on Pharmacotherapy
Vol/bind9
Udgave nummer2
Sider (fra-til)293-300
Antal sider7
ISSN1465-6566
StatusUdgivet - 2008

Bibliografisk note

Times Cited: 0ReviewEnglishRosenberg, JFrederiksberg Univ Hosp, Dept Cardiol, Nordre Fasanvej 57-59, DK-2000 Copenhagen, DenmarkCited References Count: 51258OYINFORMA HEALTHCARETELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLANDLONDON

ID: 10904942