Protein-driven inference of miRNA-disease associations

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Dokumenter

Søren Mørk, Sune Pletscher-Frankild, Albert Palleja, Jan Gorodkin, Lars Juhl Jensen

MicroRNAs (miRNAs) are a highly abundant class of non-coding RNA genes involved in cellular regulation and thus also diseases. Despite miRNAs being important disease factors, miRNA-disease associations remain low in number and of variable reliability. Furthermore, existing databases and prediction methods do not explicitly facilitate forming hypotheses about the possible molecular causes of the association, thereby making the path to experimental follow-up longer.
OriginalsprogEngelsk
TidsskriftBioinformatics (Oxford, England)
Vol/bind30
Udgave nummer3
Sider (fra-til)392-397
Antal sider6
ISSN1367-4803
DOI
StatusUdgivet - 2014

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