Paleo-eskimo mtDNA genome reveals matrilineal discontinuity in Greenland

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Marcus Thomas Pius Gilbert, Toomas Kivisild, Bjarne Grønnow, Pernille K Andersen, Ene Metspalu, Maere Reidla, Erika Tamm, Erik Axelsson, Anders Götherström, Paula F Campos, Morten Rasmussen, Mait Metspalu, Thomas F G Higham, Jean-Luc Schwenninger, Roger Nathan, Cees-Jan De Hoog, Anders Koch, Lone Nukarak Møller, Claus Andreasen, Morten Meldgaard & 3 andre Richard Villems, Christian Bendixen, Eske Willerslev

The Paleo-Eskimo Saqqaq and Independence I cultures, documented from archaeological remains in Northern Canada and Greenland, represent the earliest human expansion into the New World's northern extremes. However, their origin and genetic relationship to later cultures are unknown. We sequenced a mitochondrial genome from a Paleo-Eskimo human by using 3400-to 4500-year-old frozen hair excavated from an early Greenlandic Saqqaq settlement. The sample is distinct from modern Native Americans and Neo-Eskimos, falling within haplogroup D2a1, a group previously observed among modern Aleuts and Siberian Sireniki Yuit. This result suggests that the earliest migrants into the New World's northern extremes derived from populations in the Bering Sea area and were not directly related to Native Americans or the later Neo-Eskimos that replaced them.
OriginalsprogEngelsk
TidsskriftScience
Vol/bind320
Udgave nummer5884
Sider (fra-til)1787-1789
Antal sider3
ISSN0036-8075
DOI
StatusUdgivet - 2008

ID: 10457003