Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Magnus S. Ågren, Thomas L. Andersen, Line Andersen, Christine Bruun Schiødt, Vikas Surve, Troels T. Andreassen, Juha Risteli, Lennart E. Franzén, Jean-Marie Delaissé, Anne-Marie Heegaard, Lars Nannestad Jørgensen

Increased matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of colorectal anastomotic leakage. Tumor necrosis factor-a (TNF-a) induces MMPs and may influence anastomosis repair.
OriginalsprogEngelsk
TidsskriftInternational Journal of Colorectal Disease
Vol/bind26
Udgave nummer3
Sider (fra-til)329-337
Antal sider9
ISSN0179-1958
DOI
StatusUdgivet - 2011

ID: 32908433