Influence of intranasal and carotid cooling on cerebral temperature balance and oxygenation

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Dokumenter

Lars Nybo, Michael Wanscher, Niels H. Secher

The present study evaluated the influence of intranasal cooling with balloon catheters, increased nasal ventilation, or percutaneous cooling of the carotid arteries on cerebral temperature balance and oxygenation in six healthy male subjects. Aortic arch and internal jugular venous blood temperatures were measured to assess the cerebral heat balance and corresponding paired blood samples were obtained to evaluate cerebral metabolism and oxygenation at rest, following 60 min of intranasal cooling, 5 min of nasal ventilation, and 15 min with carotid cooling. Intranasal cooling induced a parallel drop in jugular venous and arterial blood temperatures by 0.30 ± 0.08°C (mean ± SD), whereas nasal ventilation and carotid cooling failed to lower the jugular venous blood temperature. The magnitude of the arterio-venous temperature difference across the brain remained unchanged at -0.33 ± 0.05°C following intranasal and carotid cooling, but increased to -0.44 ± 0.11°C (P
OriginalsprogEngelsk
Artikelnummer79
TidsskriftFrontiers in Physiology
Vol/bind5
Antal sider5
ISSN1664-042X
DOI
StatusUdgivet - 2014

Bibliografisk note

CURIS 2014 NEXS 057

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