A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils

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A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils. / Wilson, S.; Jones, F. M.; Fofana, H. K. M.; Landouré, A.; Kimani, G.; Mwatha, J. K.; Sacko, M.; Vennervald, Birgitte J; Dunne, D. W.

I: Parasite Immunology, Bind 35, Nr. 7-8, 2013, s. 224-228.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Wilson, S, Jones, FM, Fofana, HKM, Landouré, A, Kimani, G, Mwatha, JK, Sacko, M, Vennervald, BJ & Dunne, DW 2013, 'A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils', Parasite Immunology, bind 35, nr. 7-8, s. 224-228. https://doi.org/10.1111/pim.12035

APA

Wilson, S., Jones, F. M., Fofana, H. K. M., Landouré, A., Kimani, G., Mwatha, J. K., ... Dunne, D. W. (2013). A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils. Parasite Immunology, 35(7-8), 224-228. https://doi.org/10.1111/pim.12035

Vancouver

Wilson S, Jones FM, Fofana HKM, Landouré A, Kimani G, Mwatha JK o.a. A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils. Parasite Immunology. 2013;35(7-8):224-228. https://doi.org/10.1111/pim.12035

Author

Wilson, S. ; Jones, F. M. ; Fofana, H. K. M. ; Landouré, A. ; Kimani, G. ; Mwatha, J. K. ; Sacko, M. ; Vennervald, Birgitte J ; Dunne, D. W. / A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils. I: Parasite Immunology. 2013 ; Bind 35, Nr. 7-8. s. 224-228.

Bibtex

@article{7446407b69604f66a2fa2397d81afbe0,
title = "A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils",
abstract = "IL-33, a proposed alarmin, stimulates innate immune cells and Th2 cells to produce IL-13 and is rapidly upregulated upon antigen exposure in murine helminth infection. The human IL-33 response to helminth antigen was analysed in Malians infected with Schistosoma haematobium by disrupting parasite integrity via chemotherapy. Plasma IL-33 was measured pretreatment, and 24 h and 9 weeks post-treatment. At 24 h post-treatment, IL-33 levels were low. Nine week post-treatment IL-33 levels were elevated and were associated with an increase in intracellular IL-13 in eosinophils. Up-regulation of intracellular IL-13 in eosinophils was also associated with eosinophil expression of ST2L, the IL-33 receptor. IL-33 may play an important downstream role in the human response to schistosome adult worm antigen exposure.",
author = "S. Wilson and Jones, {F. M.} and Fofana, {H. K. M.} and A. Landour{\'e} and G. Kimani and Mwatha, {J. K.} and M. Sacko and Vennervald, {Birgitte J} and Dunne, {D. W.}",
note = "{\circledC} 2013 John Wiley & Sons Ltd.",
year = "2013",
doi = "10.1111/pim.12035",
language = "English",
volume = "35",
pages = "224--228",
journal = "Parasite Immunology",
issn = "0141-9838",
publisher = "Wiley-Blackwell",
number = "7-8",

}

RIS

TY - JOUR

T1 - A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils

AU - Wilson, S.

AU - Jones, F. M.

AU - Fofana, H. K. M.

AU - Landouré, A.

AU - Kimani, G.

AU - Mwatha, J. K.

AU - Sacko, M.

AU - Vennervald, Birgitte J

AU - Dunne, D. W.

N1 - © 2013 John Wiley & Sons Ltd.

PY - 2013

Y1 - 2013

N2 - IL-33, a proposed alarmin, stimulates innate immune cells and Th2 cells to produce IL-13 and is rapidly upregulated upon antigen exposure in murine helminth infection. The human IL-33 response to helminth antigen was analysed in Malians infected with Schistosoma haematobium by disrupting parasite integrity via chemotherapy. Plasma IL-33 was measured pretreatment, and 24 h and 9 weeks post-treatment. At 24 h post-treatment, IL-33 levels were low. Nine week post-treatment IL-33 levels were elevated and were associated with an increase in intracellular IL-13 in eosinophils. Up-regulation of intracellular IL-13 in eosinophils was also associated with eosinophil expression of ST2L, the IL-33 receptor. IL-33 may play an important downstream role in the human response to schistosome adult worm antigen exposure.

AB - IL-33, a proposed alarmin, stimulates innate immune cells and Th2 cells to produce IL-13 and is rapidly upregulated upon antigen exposure in murine helminth infection. The human IL-33 response to helminth antigen was analysed in Malians infected with Schistosoma haematobium by disrupting parasite integrity via chemotherapy. Plasma IL-33 was measured pretreatment, and 24 h and 9 weeks post-treatment. At 24 h post-treatment, IL-33 levels were low. Nine week post-treatment IL-33 levels were elevated and were associated with an increase in intracellular IL-13 in eosinophils. Up-regulation of intracellular IL-13 in eosinophils was also associated with eosinophil expression of ST2L, the IL-33 receptor. IL-33 may play an important downstream role in the human response to schistosome adult worm antigen exposure.

U2 - 10.1111/pim.12035

DO - 10.1111/pim.12035

M3 - Journal article

VL - 35

SP - 224

EP - 228

JO - Parasite Immunology

JF - Parasite Immunology

SN - 0141-9838

IS - 7-8

ER -

ID: 65708156