Predictors of 1-year visual outcome in neovascular age-related macular degeneration following intravitreal ranibizumab treatment
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Predictors of 1-year visual outcome in neovascular age-related macular degeneration following intravitreal ranibizumab treatment. / Bloch, Sara Brandi; la Cour, Morten; Sander, Birgit; Hansen, Louise K H; Fuchs, Josefine; Lund-Andersen, Henrik; Larsen, Michael.
In: Acta Ophthalmologica, 2013.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Predictors of 1-year visual outcome in neovascular age-related macular degeneration following intravitreal ranibizumab treatment
AU - Bloch, Sara Brandi
AU - la Cour, Morten
AU - Sander, Birgit
AU - Hansen, Louise K H
AU - Fuchs, Josefine
AU - Lund-Andersen, Henrik
AU - Larsen, Michael
N1 - © 2011 The Authors. Acta Ophthalmologica © 2011 Acta Ophthalmologica Scandinavica Foundation.
PY - 2013
Y1 - 2013
N2 - Purpose: To describe predictors of visual outcome in patients treated with intravitreal ranibizumab for choroidal neovascularisation (CNV) in age-related macular degeneration (AMD). Methods: Retrospective review of 279 patients with CNV in AMD who fulfilled MARINA/ANCHOR study eligibility criteria and were treated with repeated intravitreal injections of ranibizumab 0.5 mg in routine clinical practice, beginning with three initial injections at 4-week intervals followed by individualized retreatment for the subsequent 9 months. Study parameters included best-corrected visual acuity (BCVA) and morphological characteristics. Results: Mean BCVA relative to baseline was +4.7 (p 0.667) Early Treatment Diabetic Retinopathy Study letters after 3, 6 and 12 months, respectively, after a mean of 5.1 injections when the proportion of patients with BCVA =70 letters had doubled compared with baseline. Predictive factors for BCVA =35 letters after 12 months were BCVA =35 letters at baseline and month 3 (p
AB - Purpose: To describe predictors of visual outcome in patients treated with intravitreal ranibizumab for choroidal neovascularisation (CNV) in age-related macular degeneration (AMD). Methods: Retrospective review of 279 patients with CNV in AMD who fulfilled MARINA/ANCHOR study eligibility criteria and were treated with repeated intravitreal injections of ranibizumab 0.5 mg in routine clinical practice, beginning with three initial injections at 4-week intervals followed by individualized retreatment for the subsequent 9 months. Study parameters included best-corrected visual acuity (BCVA) and morphological characteristics. Results: Mean BCVA relative to baseline was +4.7 (p 0.667) Early Treatment Diabetic Retinopathy Study letters after 3, 6 and 12 months, respectively, after a mean of 5.1 injections when the proportion of patients with BCVA =70 letters had doubled compared with baseline. Predictive factors for BCVA =35 letters after 12 months were BCVA =35 letters at baseline and month 3 (p
U2 - 10.1111/j.1755-3768.2011.02268.x
DO - 10.1111/j.1755-3768.2011.02268.x
M3 - Journal article
C2 - 22008284
JO - Acta Ophthalmologica
JF - Acta Ophthalmologica
SN - 1755-375X
ER -
ID: 40149354