Familial Aggregation of Lone Atrial Fibrillation in Young Persons

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Standard

Familial Aggregation of Lone Atrial Fibrillation in Young Persons. / Oyen, Nina; Ranthe, Mattis F; Carstensen, Lisbeth; Boyd, Heather A; Olesen, Morten S; Olesen, Søren-Peter; Wohlfahrt, Jan; Melbye, Mads.

I: Journal of the American College of Cardiology, Bind 60, Nr. 10, 2012, s. 917-21.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Oyen, N, Ranthe, MF, Carstensen, L, Boyd, HA, Olesen, MS, Olesen, S-P, Wohlfahrt, J & Melbye, M 2012, 'Familial Aggregation of Lone Atrial Fibrillation in Young Persons', Journal of the American College of Cardiology, bind 60, nr. 10, s. 917-21. https://doi.org/10.1016/j.jacc.2012.03.046

APA

Oyen, N., Ranthe, M. F., Carstensen, L., Boyd, H. A., Olesen, M. S., Olesen, S-P., Wohlfahrt, J., & Melbye, M. (2012). Familial Aggregation of Lone Atrial Fibrillation in Young Persons. Journal of the American College of Cardiology, 60(10), 917-21. https://doi.org/10.1016/j.jacc.2012.03.046

Vancouver

Oyen N, Ranthe MF, Carstensen L, Boyd HA, Olesen MS, Olesen S-P o.a. Familial Aggregation of Lone Atrial Fibrillation in Young Persons. Journal of the American College of Cardiology. 2012;60(10):917-21. https://doi.org/10.1016/j.jacc.2012.03.046

Author

Oyen, Nina ; Ranthe, Mattis F ; Carstensen, Lisbeth ; Boyd, Heather A ; Olesen, Morten S ; Olesen, Søren-Peter ; Wohlfahrt, Jan ; Melbye, Mads. / Familial Aggregation of Lone Atrial Fibrillation in Young Persons. I: Journal of the American College of Cardiology. 2012 ; Bind 60, Nr. 10. s. 917-21.

Bibtex

@article{f5100a456023428fbf8323adfc03dd1d,
title = "Familial Aggregation of Lone Atrial Fibrillation in Young Persons",
abstract = "OBJECTIVES: We investigated whether an individual's risk of developing lone atrial fibrillation (AF) before age 60 years is associated with lone AF in relatives. BACKGROUND: Genetic factors may play a role in the development of lone AF. METHODS: Using Danish national registers, a cohort was established of ~4 million persons born between 1950 and 2008, and those with a family history of lone AF (AF without preceding cardiovascular/endocrine diagnoses) were identified. Individuals were followed up until the first diagnosis of lone AF. Poisson regression was used to estimate incidence rate ratios (IRRs). RESULTS: In ~92 million person-years of follow-up, 9,507 persons were identified as having lone AF. The IRRs for lone AF given an affected first- or second-degree relative were 3.48 (95% confidence interval [CI]: 3.08 to 3.93) and 1.64 (95% CI: 1.04 to 2.59), respectively. IRRs were higher for men than for women but were not associated with the affected relative's sex. IRR for lone AF was 6.24 (95% CI: 2.59 to 15.0), given at least 2 first-degree relatives affected with lone AF. The IRR for lone AF in persons aged ",
author = "Nina Oyen and Ranthe, {Mattis F} and Lisbeth Carstensen and Boyd, {Heather A} and Olesen, {Morten S} and S{\o}ren-Peter Olesen and Jan Wohlfahrt and Mads Melbye",
note = "Copyright {\textcopyright} 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.",
year = "2012",
doi = "10.1016/j.jacc.2012.03.046",
language = "English",
volume = "60",
pages = "917--21",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier",
number = "10",

}

RIS

TY - JOUR

T1 - Familial Aggregation of Lone Atrial Fibrillation in Young Persons

AU - Oyen, Nina

AU - Ranthe, Mattis F

AU - Carstensen, Lisbeth

AU - Boyd, Heather A

AU - Olesen, Morten S

AU - Olesen, Søren-Peter

AU - Wohlfahrt, Jan

AU - Melbye, Mads

N1 - Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

PY - 2012

Y1 - 2012

N2 - OBJECTIVES: We investigated whether an individual's risk of developing lone atrial fibrillation (AF) before age 60 years is associated with lone AF in relatives. BACKGROUND: Genetic factors may play a role in the development of lone AF. METHODS: Using Danish national registers, a cohort was established of ~4 million persons born between 1950 and 2008, and those with a family history of lone AF (AF without preceding cardiovascular/endocrine diagnoses) were identified. Individuals were followed up until the first diagnosis of lone AF. Poisson regression was used to estimate incidence rate ratios (IRRs). RESULTS: In ~92 million person-years of follow-up, 9,507 persons were identified as having lone AF. The IRRs for lone AF given an affected first- or second-degree relative were 3.48 (95% confidence interval [CI]: 3.08 to 3.93) and 1.64 (95% CI: 1.04 to 2.59), respectively. IRRs were higher for men than for women but were not associated with the affected relative's sex. IRR for lone AF was 6.24 (95% CI: 2.59 to 15.0), given at least 2 first-degree relatives affected with lone AF. The IRR for lone AF in persons aged

AB - OBJECTIVES: We investigated whether an individual's risk of developing lone atrial fibrillation (AF) before age 60 years is associated with lone AF in relatives. BACKGROUND: Genetic factors may play a role in the development of lone AF. METHODS: Using Danish national registers, a cohort was established of ~4 million persons born between 1950 and 2008, and those with a family history of lone AF (AF without preceding cardiovascular/endocrine diagnoses) were identified. Individuals were followed up until the first diagnosis of lone AF. Poisson regression was used to estimate incidence rate ratios (IRRs). RESULTS: In ~92 million person-years of follow-up, 9,507 persons were identified as having lone AF. The IRRs for lone AF given an affected first- or second-degree relative were 3.48 (95% confidence interval [CI]: 3.08 to 3.93) and 1.64 (95% CI: 1.04 to 2.59), respectively. IRRs were higher for men than for women but were not associated with the affected relative's sex. IRR for lone AF was 6.24 (95% CI: 2.59 to 15.0), given at least 2 first-degree relatives affected with lone AF. The IRR for lone AF in persons aged

U2 - 10.1016/j.jacc.2012.03.046

DO - 10.1016/j.jacc.2012.03.046

M3 - Journal article

C2 - 22726627

VL - 60

SP - 917

EP - 921

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 10

ER -

ID: 38505698