Enteroantigen-presenting B cells efficiently stimulate CD4(+) T cells in vitro
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Enteroantigen-presenting B cells efficiently stimulate CD4(+) T cells in vitro. / Schmidt, Esben Gjerløff Wedebye; Kristensen, Nanna Ny; Claesson, Mogens Helweg; Pedersen, Anders Elm.
I: Inflammatory Bowel Diseases, Bind 17, Nr. 1, 2011, s. 308-18.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Enteroantigen-presenting B cells efficiently stimulate CD4(+) T cells in vitro
AU - Schmidt, Esben Gjerløff Wedebye
AU - Kristensen, Nanna Ny
AU - Claesson, Mogens Helweg
AU - Pedersen, Anders Elm
N1 - Copyright © 2010 Crohn's & Crohn's & Colitis Foundation of America, Inc.
PY - 2011
Y1 - 2011
N2 - Presentation of enterobacterial antigens by antigen-presenting cells and activation of enteroantigen-specific CD4(+) T cells are considered crucial steps in inflammatory bowel disease (IBD) pathology. The detrimental effects of such CD4(+) T cells have been thoroughly demonstrated in models of colitis. Also, we have previously established an in vitro assay where murine enteroantigen-specific colitogenic CD4(+) CD25(-) T cells are activated by splenocytes pulsed with an enterobacterial extract.
AB - Presentation of enterobacterial antigens by antigen-presenting cells and activation of enteroantigen-specific CD4(+) T cells are considered crucial steps in inflammatory bowel disease (IBD) pathology. The detrimental effects of such CD4(+) T cells have been thoroughly demonstrated in models of colitis. Also, we have previously established an in vitro assay where murine enteroantigen-specific colitogenic CD4(+) CD25(-) T cells are activated by splenocytes pulsed with an enterobacterial extract.
U2 - 10.1002/ibd.21429
DO - 10.1002/ibd.21429
M3 - Journal article
C2 - 20722062
VL - 17
SP - 308
EP - 318
JO - Inflammatory Bowel Diseases
JF - Inflammatory Bowel Diseases
SN - 1078-0998
IS - 1
ER -
ID: 32242512